Dermal stem cells help regenerate hair follicles and heal skin wounds.
35 citations
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January 2020 in “Skin Pharmacology and Physiology” The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.
3 citations
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February 2021 in “Experimental dermatology” Dermal papilla microtissues could be useful for initial hair growth drug testing.
18 citations
,
January 1994 in “Skin Pharmacology and Physiology” Human dermal fibroblasts and hair papilla cells help outer root sheath cells grow and develop properly.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Dermal papilla cell-derived exosomes can help stem cells grow hair.
The treatment successfully integrated hair follicles into a dermal template, showing new hair growth and blood vessel formation.
April 2016 in “Journal of Investigative Dermatology” Removing alkaline phosphatase from human skin cells hinders the creation of new hair follicles.
13 citations
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June 2007 in “Journal of Dermatological Science” Researchers created a cell line to study hair growth and found specific genes affected by dihydrotestosterone.
15 citations
,
August 2013 in “Stem Cells and Development” The method increases stem-like cells for better skin regeneration.
9 citations
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March 2013 in “Expert opinion on biological therapy” Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
November 2023 in “Experimental Dermatology” Exosomes from human hair follicle cells can improve aging hair follicle cell function and help regenerate hair follicles.
18 citations
,
July 2012 in “Cell Biology International Reports” Human mesenchymal stem cells can become dermal papilla cells, aiding hair growth.
3 citations
,
February 2009 in “Chinese Journal of Traumatology (english Edition)” Human hair cells can be used to grow new hair on rat ears, suggesting a possible treatment for hair loss.
September 2019 in “Journal of Investigative Dermatology” Researchers developed a 3D skin model with its own immune and blood vessel cells to better understand skin health and disease.
28 citations
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January 2013 in “Stem cells” Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The research identified specific genes that are active in the cells crucial for hair growth.
April 2017 in “Journal of Investigative Dermatology” Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.
4 citations
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January 2022 in “Journal of Bioscience and Bioengineering” Electric stimulation can increase hair growth by activating certain genes in skin cells.
1 citations
,
July 2025 in “Scientific Reports” CD133+ cells are crucial for hair growth.
135 citations
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January 1996 in “Journal of Investigative Dermatology”
2 citations
,
August 2011 in “InTech eBooks” New methods for growing skin cells can improve skin grafts by building blood vessels within them.
Human dermal papilla cell vesicles can reduce skin fibrosis in mice.
6 citations
,
February 2014 in “Experimental Dermatology” Hair follicle regeneration is possible but challenging, especially in humans, due to the need for specific cells and a better understanding of how they signal growth.
32 citations
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April 2017 in “Scientific Reports” Platelet-rich plasma can help grow more mouse hair follicles, but it doesn't work for human hair follicles yet.
2 citations
,
January 2022 in “Oxidative Medicine and Cellular Longevity” Exosomes from dermal papilla cells help hair follicle stem cells grow and survive.
13 citations
,
May 2005 in “Seminars in Plastic Surgery” Follicular Cell Implantation might become a new treatment for hair loss and could lead to advances in organ regeneration.
184 citations
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December 2018 in “Nature Communications” Researchers created human hair follicles using a new method that could help treat hair loss.
5 citations
,
March 2020 in “Cell and Tissue Banking” Injected cells show potential for hair growth.
57 citations
,
November 1998 in “Wound Repair and Regeneration” Hair papilla cells can create and regenerate hair bulbs under the right conditions.
January 2008 in “Journal of Practical Medical Techniques” Microencapsulated cells can regenerate hair follicles in rat ears.