research Mechanical and Immunological Regulation in Wound Healing and Skin Reconstruction
Advances in mechanobiology and immunology could lead to scarless wound healing.
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research Epidermal keratinocyte stem cells: their maintenance and regulation
Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
research Lactate in skin homeostasis: metabolism, skin barrier, and immunomodulation
Lactate is vital for skin health, influencing metabolism, the skin barrier, immune responses, and has therapeutic potential for skin disorders.
research Molecular and spatial design of early skin development
The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
research Ox40-Cre–mediated deletion of BRD4 reveals an unexpected phenotype of hair follicle stem cells in alopecia
Deleting the BRD4 protein in certain skin cells causes hair loss and skin inflammation.
research Bio-Nanovesicle-Based Approaches for Hair and Skin Regeneration: An Updated Concise Review
Bio-nanovesicles could improve hair and skin regeneration by delivering important molecules to repair and heal.
research Adipose tissue remodeling via TSLP-mediated IL-4/IL-13 signaling: Implications for atopic dermatitis and skin barrier
TSLP affects atopic dermatitis by increasing sebum and reducing fat through IL-4/IL-13 signaling.
research Zinc, Copper, and Iron in Selected Skin Diseases
Zinc, copper, and iron are important for skin health and may help diagnose skin diseases.
research Translational frontiers: insight from lymphatics in skin regeneration
Lymphatic vessels are important for skin repair and could affect skin disease treatments.
research Deciphering the molecular mechanisms of stem cell dynamics in hair follicle regeneration
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
research Skin Commensal Antigens: Taking the Road Less Traveled
Skin bacteria can help wound healing by activating certain immune cells.
research Perforins Expression by Cutaneous Gamma Delta T Cells
Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.
research The role of zinc in skin physiology – relevance for the pathogenesis and treatment of vitiligo
Zinc may be linked to vitiligo development and severity, but its role is not fully understood and zinc supplementation benefits are unclear.
research MSC-derived sEV-loaded hyaluronan hydrogel promotes scarless skin healing by immunomodulation in a large skin wound model
A special gel helps heal skin wounds without scars by calming the immune response.
research Whole-genome bisulfite sequencing of goat skins identifies signatures associated with hair cycling
DNA methylation changes are linked to hair growth cycles in goats.
research Microneedle‐mediated Delivery of Immunomodulators Restores Immune Privilege in Hair Follicles and Reverses Immune‐Mediated Alopecia
A microneedle patch can help regrow hair by restoring immune balance in hair follicles.
research Phospholipase's role in maintaining and restoring skin and hair health
Phospholipases help maintain and restore skin and hair health, potentially leading to new treatments for related conditions.
research A Novel Crosslinking Approach for Biomanufacturing of a Collagen‐Based Skin Dermal Template
The new collagen template speeds up production and supports skin healing without harmful reactions.
research Modern aspects of external application and prospects of using the secretome of mesenchymal stem cells (review)
Mesenchymal stem cell secretome shows promise for skin treatments but needs more human trials.
research 175 Understanding immune privilege in an inducible mouse model of primary cicatrcial alopecia
The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.
research Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog (Atelerix albiventris)
The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.
research Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin
Hair follicles help attract immune cells to the skin during stress.
research Pathomechanisms of immune-mediated alopecia
The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.
research Regulatory T cells in inflammatory skin disease: from mice to humans
Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.
research Advances in Microengineered Platforms for Skin Research
Skin-on-a-chip devices better mimic human skin for research.
research Delayed Collagen Production without Myofibroblast Formation Contributes to Reduced Scarring in Adult Skin Microwounds
Microthermal wounds heal with less scarring due to delayed collagen production and minimal inflammation.
research 054 Deep Analysis of CD4+ Trm Cells in Normal and Atopic Dermatitis Human Skin
Certain immune cells in atopic dermatitis skin could be targeted for treatment.
research Deciphering the functions of the hair follicle infundibulum in skin physiology and disease
The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
research 546 Epidermal growth factor receptor as a key regulator of the immune privilege
EGFR is crucial for preventing hair follicle inflammation and hair loss.
research 014 Tyrosine Kinase 2 Inhibition Ameliorates the Phenotype of Lesional Alopecia Areata Scalp Skin Ex Vivo, and Reverses the Induction of Human Alopecia Areata in a Humanized Mouse Model
TYK2 inhibition may help treat alopecia areata by promoting hair growth and reducing immune response.