December 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Hidradenitis suppurativa may be a type of autoinflammatory skin disease linked to gene mutations and immune system issues.
The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.
223 citations
,
January 2000 in “BioFactors” Food-derived peptides may help prevent diseases like high blood pressure and high cholesterol, and can support the immune system.
6 citations
,
June 2015 in “Journal of theoretical biology” The model showed that immune system guardians and the cytokine interferon-γ are key in alopecia areata progression.
The nail immune system is similar to hair but different from skin, with fewer immune markers.
4 citations
,
July 2021 in “Skin Appendage Disorders” Sudden hair whitening may be linked to immune system activity.
60 citations
,
August 2005 in “Endocrinology” αMSH may help regulate immune responses in hair follicles and its disruption could lead to hair loss.
2 citations
,
February 2025 Merkel cell polyomavirus can infect and persist in skin cells, evading the immune system, but certain treatments can control it.
March 2025 in “Frontiers in Cell and Developmental Biology” Improving nerve and immune interactions may help heal chronic wounds.
January 2026 in “Chemical Engineering Journal” Engineered nanovesicles from hair follicle stem cells enable scarless healing of infected wounds.
Researchers made a mouse model with curly hair and hair loss by editing a gene.
May 2023 in “Elsevier eBooks” Some treatments that modify the immune system might help with certain types of hair loss but haven't been explored for common hair loss alone.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The study suggests that changes in immune system receptors and their interaction with a cell component may be important in the development of a type of hair loss condition.
38 citations
,
March 2015 in “Journal of controlled release” IMSG nanoparticles improve vaccine delivery and immune response through hair follicles.
June 2025 in “International Journal of Clinical Medical Research” Healthcare professionals need better training and systems for drug interaction reporting, injectable vitamin B12 helps tingling, oral helps numbness, probiotics may help ulcerative colitis, and more research is needed on Post-Finasteride Syndrome.
1 citations
,
February 2018 in “Orthopedics and rheumatology” Combining Western chemotherapy with Traditional Chinese Medicine can reduce side effects and improve immune response in treating bone and soft tissue tumors.
375 citations
,
July 2006 in “Journal of Investigative Dermatology” Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
January 2026 in “Dermatologic Therapy” Current models for studying alopecia are inadequate, and more human-like systems are needed.
16 citations
,
June 2017 in “Advances in Therapy” New treatments for hair loss are showing promise due to better understanding of genetics and the immune system.
510 citations
,
August 2006 in “Endocrinology” The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Hidradenitis suppurativa is a chronic skin disorder linked to genetics, lifestyle, and immune issues, treatable with medications and surgery.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Hidradenitis suppurativa is a chronic skin disorder linked to genetics, lifestyle, and immune issues, treatable with medication and sometimes surgery.
May 2025 in “Immunotherapy” Patients were very satisfied with hair regrowth after taking ritlecitinib for alopecia areata.
November 2003 in “Journal of Investigative Dermatology” Topical Imiquimod may fight vascular tumors by affecting blood vessels or the immune system, low iron might be linked to some hair loss, removing the top skin layer helps vitamin C get in, genetic testing helps diagnose skin conditions, and too much iron could worsen skin inflammation.
November 2015 in “Chemical & engineering news” Certain topical drugs can regrow hair in mice.
135 citations
,
May 1994 in “Medical Entomology and Zoology” Mouse models help study genetic skin diseases.
January 2026 in “Journal of Investigative Dermatology” Female-pattern hair loss may involve an autoimmune-like process, suggesting new treatment options.
January 2021 in “Zenodo (CERN European Organization for Nuclear Research)” Natural remedies like essential oils are preferred for safe and beneficial hair growth support.
August 1994 in “Journal of dermatological science” Cyclosporin A and FK506 can start new hair growth in mice, but ascomycin and rapamycin cannot.
3 citations
,
September 2021 in “JAAD case reports” Denosumab, a bone loss treatment, may cause hair loss and skin reactions due to immune system effects.