research 0041 Comparative multi-omics highlights inflammatory monocyte-derived dendritic cells as key mediators of UVB-induced photosensitivity
Monocyte-derived dendritic cells play a key role in UVB-induced skin sensitivity and inflammation.
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research Choreographing Immunity in the Skin Epithelial Barrier
The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
research Converging physiological roles of the anthrax toxin receptors
CMG2 and TEM8 receptors have distinct roles in skin and growth disorders, affecting collagen breakdown and growth.
research Non-pigmentary actions of alpha-melanocyte-stimulating hormone--lessons from the cutaneous melanocortin system.
Alpha-melanocyte-stimulating hormone helps manage skin inflammation and protect against UV damage.
research Macrophage-Centric Immunometabolic Crosstalk in Alopecia Areata Pathogenesis: Mechanisms and Therapeutic Implications
research Cutaneous manifestations associated with immune checkpoint inhibitors
Immune checkpoint inhibitors can cause skin issues but are linked to better cancer outcomes.
research Identifying effective immune biomarkers in alopecia areata diagnosis based on machine learning methods
Machine learning can help find new ways to treat alopecia areata.
research Macrophages as central mediators of sympathetic neuro-immune interplay in autoimmunity
Restoring nerve-macrophage communication may help treat autoimmune diseases.
research A case of multifocal acquired demyelinating sensory and motor neuropathy with whole body alopecia
Immunological treatment improved both neuropathy and alopecia.
research The role of PPARγ-mediated signalling in skin biology and pathology: new targets and opportunities for clinical dermatology
PPARγ is crucial for skin health but can have both beneficial and harmful effects.
research 1391 Immune cells may have a role in hair loss process caused by TRPV3 gain-of-function mutation
Immune cells might contribute to hair loss caused by a specific mutation.
research Exploring the Overlooked Roles and Mechanisms of Fibroblasts in the Foreign Body Response
Fibroblasts play a crucial role in the body's response to implants, needing more research for better treatments.
research Editors' Picks
Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.
research Dissecting the Roles of Innate Cells in the Skin and Intractable Skin Diseases
Hair follicles regulate immune cells in the skin, and disrupting certain pathways can lead to skin issues and infections.
research Conserved γδ T cell selection by BTNL proteins limits progression of human inflammatory bowel disease
BTNL proteins help control inflammatory bowel disease by maintaining specific immune cells.
research SnapshotDx Quiz: May 2020
BIVV009 is a safe treatment for bullous pemphigoid that reduces C3 deposition without harmful side effects.
research 0282 Effect of systemic immunomodulators on incidence of alopecia areata: A retrospective cohort study
Leflunomide may reduce the risk of alopecia areata, while methotrexate, cyclosporine, and rituximab may increase it.
research Multiple sclerosis disease-modifying therapies: adverse effect surveillance and management
The document concludes that managing side effects of MS therapies is crucial for treatment success and patient adherence.
research TGFβ and cancer metastasis: an inflammation link
TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
research The Role of Janus Kinase Inhibitors in Dermatology
Janus Kinase Inhibitors are promising new treatments for various skin conditions due to their effectiveness and safety.
research Immune and Non-immune Interactions in the Pathogenesis of Androgenetic Alopecia
research Functionalised-biomatrix for wound healing and cutaneous regeneration: future impactful medical products in clinical translation and precision medicine
The document concludes that more research is needed on making and understanding biomaterial scaffolds for wound healing.
research Systemic Autoimmune Diseases
The document concludes that systemic autoimmune diseases are complex, incurable, and require ongoing treatment and research.
research EMATOPOIESIS REVOLVES AROUND THE PRIMORDIALEVOLUTIONAL RHYTHM OF INNATE IMMUNITY AND PURINERGIC SIGNALING – A JOURNEY TO THE DEVELOPMENTAL ROOTS
Ancient immune and signaling pathways still regulate blood cell development.
research The BIOMarkers in Atopic Dermatitis and Psoriasis (BIOMAP) glossary: developing a lingua franca to facilitate data harmonization and cross‐cohort analyses
The BIOMAP glossary standardizes data to improve research on atopic dermatitis and psoriasis.
research Distinct use of super-enhancer elements controls cell type–specific CD25 transcription and function
Super-enhancers control CD25 expression in specific cell types, affecting immune function.
research Sequential Immunotherapy with Tofacitinib and Low-Dose IL-2 Induces Sustained Remission in Alopecia Areata: A Proof-of-concept monocentric study
Tofacitinib and low-dose IL-2 may help maintain hair regrowth in alopecia areata without ongoing treatment.
research Targeting of Skin Antigen-Presenting Cells
Transcutaneous vaccination using nanoparticles can enhance immune responses and reduce basal cell carcinomas.
research IMMUNOLOGICAL AND GENETIC ASPECTS OF HEREDITARY ANTIBODY DEFICIENCIES
Children with frequent severe infections and low antibodies should be checked for immune deficiencies.
research ГНОТОБИОНТЫ – ЭКСПЕРИМЕНТАЛЬНАЯ МОДЕЛЬ
Controlled microflora in animals delays immune cell maturation and affects immunity.