18 citations
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April 2001 in “Bioorganic & Medicinal Chemistry Letters” The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.
2 citations
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July 2020 in “Journal of Applied Pharmaceutical Science” Natural ingredients can improve skin and hair, but more research is needed.
416 citations
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September 1997 in “Journal of Investigative Dermatology” People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
324 citations
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July 2020 in “Applied Water Science” Water near Abakaliki mines has high toxic metal levels, posing health risks.
113 citations
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April 1999 in “The Journal of Clinical Endocrinology and Metabolism” Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.
108 citations
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January 2003 in “Journal of Cosmetic Dermatology” Wrinkles form due to structural skin changes and vary in type and treatment response.
98 citations
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May 2008 in “Archives of Dermatological Research” Eclipta alba extract helps hair grow faster and more effectively than minoxidil in rats.
93 citations
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February 2008 in “Atmospheric environment” Ozone reacts more with unwashed hair, producing compounds due to scalp oils, which could lower ozone exposure but increase exposure to reaction products.
78 citations
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January 2000 in “Gynecological Endocrinology” Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.
77 citations
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January 2015 in “International Journal of Biological Macromolecules” Chitosan nanoparticles improve minoxidil delivery to hair follicles for better alopecia treatment.
64 citations
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March 2006 in “Food Chemistry” The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.
61 citations
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September 2020 in “Bioactive Materials” A special dressing called FEA-PCEI can speed up wound healing, reduce scars, and help grow new hair follicles, but only at the right dosage.
58 citations
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January 2003 in “Biological & Pharmaceutical Bulletin” Bombax ceiba stem bark extracts can lower blood pressure, but high doses can be toxic and lethal.
53 citations
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June 1993 in “Proceedings of the National Academy of Sciences of the United States of America” LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
47 citations
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July 1967 in “Science” Not eating enough protein can cause hair roots to shrink and lose color, and hair to become thinner.
46 citations
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August 1990 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.
45 citations
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August 2010 in “Hormone Molecular Biology and Clinical Investigation” Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.
36 citations
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September 2013 in “PLoS ONE” Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.
35 citations
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June 2017 in “Pharmacognosy Journal” Eclipta alba leaves have compounds that can fight certain harmful bacteria.
34 citations
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March 2004 in “Journal of Liposome Research” Minoxidil-loaded liposomes effectively deliver to hair follicles, potentially improving hair growth and treating alopecia.
31 citations
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June 2017 in “Regeneration” BMP2 needs periosteal tissue to help regenerate mouse middle finger bones within a specific time.
31 citations
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December 2002 in “Biochimica et biophysica acta. G, General subjects/Biochimica et biophysica acta. General subjects (Online)” The research found two types of calcium in human hair, one that varies among individuals and another that is consistent across people.
28 citations
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September 2020 in “Pharmaceutics” 3D-printed mesoporous scaffolds show promise for personalized drug delivery with controlled release.
27 citations
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April 2020 in “Molecular Biology and Evolution” Ancient Chinese goats evolved cashmere-producing traits due to selective breeding, particularly in genes affecting hair growth.
27 citations
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May 2006 in “Biochemical and Biophysical Research Communications” Wnt-10b is important for starting hair growth and developing hair follicles.
27 citations
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October 2001 in “Journal of Medicinal Chemistry” Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.
25 citations
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August 2015 in “International Journal of Cosmetic Science” Malva verticillata seed extract might help treat hair loss by activating hair growth signals in skin cells.
24 citations
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August 2018 in “Journal of Ayurvedic and herbal medicine” Hibiscus rosa-sinensis may help treat various health issues and promote hair growth, but more research is needed for safety.
24 citations
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January 2015 in “Annals of Dermatology” Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.
23 citations
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April 1999 in “The Journal of Clinical Endocrinology and Metabolism” All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.