March 2024 in “BMC women's health” The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.
September 2009 in “Annales D Endocrinologie” DHEA supplementation may improve quality of life, neuropsychological functions, and sexual satisfaction in individuals with adrenal insufficiency, but more research is needed to confirm its safety and effectiveness.
14 citations
,
September 1983 in “Acta Dermato Venereologica” Citral increases sebaceous gland activity in male rats.
1 citations
,
January 2022 in “Transgender health” Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.
14 citations
,
May 2022 in “Frontiers in Endocrinology” Lower testosterone levels increase kidney stone risk in men over 40.
306 citations
,
August 2011 in “Journal of cachexia, sarcopenia and muscle” Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.
24 citations
,
July 1980 in “Journal of Toxicology and Environmental Health” High doses of norethindrone acetate in rats caused various organ changes but didn't significantly increase tumor rates.
18 citations
,
January 2022 in “Clinical Epidemiology” Higher doses of glucocorticoids increase the risk of blood clots in asthma patients.
14 citations
,
October 2022 in “Journal of the American Heart Association” Lower testosterone levels may increase heart failure risk in older men.
11 citations
,
November 2017 in “Hong Kong Medical Journal” Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.
10 citations
,
January 2019 in “Archives of Endocrinology and Metabolism” Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.
7 citations
,
July 2024 in “Frontiers in Immunology” COVID-19 can increase the risk of hair loss, especially in people over 40.
6 citations
,
March 2021 in “Frontiers in surgery” A woman's symptoms of increased body hair and testosterone were caused by a rare adrenal tumor, which was removed successfully.
5 citations
,
March 2021 in “F1000Research” A specific gene variation increases the risk of high uric acid and cholesterol in young Mexican males.
2 citations
,
September 2021 in “F1000Research” The ABCG2 gene variant increases the risk of high uric acid and cholesterol, especially in overweight or obese young Mexican males.
2 citations
,
March 2022 in “Applied sciences” Lespedeza bicolor extract promotes hair growth and increases hair follicle cell growth, potentially making it a better treatment than minoxidil.
1 citations
,
August 2017 in “Journal of food and nutrition research” The herbal supplement increased hair thickness and reduced scalp oiliness in women.
January 2026 in “Dermatologic Therapy” Botulinum Toxin Type A can increase hair density and improve hair thickness in androgenetic alopecia with minimal side effects.
May 2024 in “JAMA Dermatology” Oral contraceptive use may increase the risk of frontal fibrosing alopecia in women with a specific CYP1B1 gene variant.
April 2024 in “Frontiers in microbiology” Certain gut bacteria may increase or decrease the risk of male pattern baldness.
November 2023 in “British journal of nutrition” Curcumin supplements increase adiponectin and decrease leptin in adults.
November 2023 in “Advanced Science” A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
September 2023 in “F&S reports” PCOS may increase the risk of mental health issues like depression and anxiety.
July 2023 in “International journal of trichology” Cellcurin therapy with microneedling increases hair density and thickness in treating hair loss in men and women.
April 2020 in “Online journal of complementary & alternative medicine” Some medications can help increase sexual desire and function in women.
May 2023 in “Research and Practical Medicine Journal” Severe COVID-19 may increase lung cancer risk and affect treatment in women due to hormonal changes.
338 citations
,
April 2001 in “Current Biology” c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.
222 citations
,
August 2014 in “Cell Metabolism” Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.
182 citations
,
June 2002 in “Journal of Neuroscience” Androgens can help prevent memory problems caused by apoE4.
38 citations
,
April 2021 in “JAMA Network Open” Higher variability in systolic blood pressure increases long-term mortality risk in coronary artery disease patients.