research Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex
Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
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930-960 / 1000+ resultsresearch Newer approaches to dry eye therapy: Nanotechnology, regenerative medicine, and tissue engineering
New treatments using advanced technology aim to improve dry eye disease care.
research Pleiotropic Role of Notch Signaling in Human Skin Diseases
Notch signaling disruptions can cause various skin diseases.
research SOCS1 and SOCS3 as key checkpoint molecules in the immune responses associated to skin inflammation and malignant transformation
SOCS1 and SOCS3 help control skin inflammation and are important for developing treatments for skin diseases.
research Regulatory T cells in dominant immunologic tolerance
Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.
research Multifunctional antibacterial bioactive nanoglass hydrogel for normal and MRSA infected wound repair
The hydrogel speeds up healing of normal and MRSA-infected wounds.
research Recent Advances in the Use of Cubosomes as Drug Carriers with Special Emphasis on Topical Applications
Cubosomes improve drug delivery for skin and eye diseases by enhancing adhesion, retention, and release.
research Bubble-Based Drug Delivery Systems: Next-Generation Diagnosis to Therapy
Bubble-based systems show promise for precise, targeted drug delivery and diagnosis, especially in cancer treatment.
research Hyaluronic Acid Micelles for Promoting the Skin Permeation and Deposition of Curcumin
CUR-loaded micelles improve skin delivery and effects of curcumin for pain and infections.
research Thiazole: A Versatile Standalone Moiety Contributing to the Development of Various Drugs and Biologically Active Agents
Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.
research Engineering Cell Surfaces with Polyelectrolyte Materials for Translational Applications
Polyelectrolytes can improve cell surfaces for better medical applications.
research Type 1 Diabetes Mellitus and Autoimmune Diseases: A Critical Review of the Association and the Application of Personalized Medicine
Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.
research Proteolysis‐Targeting Chimera (PROTAC): Current Applications and Future Directions
PROTACs offer new ways to treat hard-to-target diseases, with promising drugs for cancer in advanced trials.
research The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes
Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.
research Docosahexaenoic acid slows inflammation resolution and impairs the quality of healed skin tissue
High DHA levels delay wound healing and worsen skin repair quality.
research Type 1 interferon signature and cytotoxic T lymphocyte activation targeted against sweat ducts in inflammatory acquired idiopathic generalized anhidrosis
Inflammation damages sweat ducts, causing sweat gland injury.
research Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases
Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.
research Organic and Biogenic Nanocarriers as Bio-Friendly Systems for Bioactive Compounds’ Delivery: State-of-the Art and Challenges
Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.
research Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time
Advanced imaging methods have improved understanding of cancer cell interactions and treatment strategies.
research The Role of Natural Hydrogels in Enhancing Wound Healing: From Biomaterials to Bioactive Therapies
Natural hydrogels can improve wound healing but face challenges in becoming widely used in clinics.
research Confocal Laser Scanning Microscopy as a Tool for the Investigation of Skin Drug Delivery Systems and Diagnosis of Skin Disorders
Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
research Usefulness of Dermoscopy to Provide Accurate Assessment of Skin Cancers
Dermoscopy is an effective tool for accurately detecting skin cancers.
research Advances in Laser Therapy for Hidradenitis Suppurativa: A Systematic Assessment of Current Evidence
Laser therapy effectively treats all stages of hidradenitis suppurativa, offering a reliable alternative to medication.
research Combined Systemic and Cutaneous Ovalbumin–Aluminum Sensitization Triggers Thermal Hyperalgesia, Spinal Gliosis, and Nociceptive Nerve Fibers Sprouting in Mice
Ovalbumin–aluminum sensitization causes increased pain sensitivity and nerve changes in mice.
research Aging of the Human Lip: Current Knowledge and Clinical Implications
Lip aging differs from facial aging, needing specific care for barrier, wrinkles, and pigment changes.
research Exploring the Impact of Systemic Inflammatory Regulators on Rosacea Risk: A Bidirectional Mendelian Randomization Analysis
Higher levels of certain proteins may increase or decrease rosacea risk.
research Platelet-Rich Plasma in Dermatology: New Insights on the Cellular Mechanism of Skin Repair and Regeneration
PRP helps skin heal, possibly through special cells called telocytes.
research Composite Hydrogels with Embedded Silver Nanoparticles and Ibuprofen as Wound Dressing
The hydrogel with silver and ibuprofen promotes wound healing and fights infection.
research Acne Syndromes and Mosaicism
Understanding how acne develops in different diseases could lead to new treatments.