research The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier
IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.
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research Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research The Epidermal Vitamin D System and Innate Immunity: Some More Light Shed on This Unique Photoendocrine System?
Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.
research Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis
A specific group of immune and skin cells may cause chronic inflammation in atopic dermatitis.
research Dermal White Adipose Tissue: A Newly Recognized Layer of Skin Innate Defense
Skin fat plays a key role in immune defense and healing beyond just storing energy.
research Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes
Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.
research CAQ Corner: Basic concepts of transplant immunology
The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.
research Novel acquisitions on the immunoprotective roles of the EGF receptor in the skin
EGF receptor is crucial for skin health and its inhibitors can cause skin rashes.
research New insights into inflammatory memory of epidermal stem cells
Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
research Local IL-17 orchestrates skin aging
Blocking IL-17 signaling can delay skin aging and improve skin and hair health.
research Nitric Oxide Signal Transduction and Its Role in Skin Sensitization
Nitric oxide is important for skin functions and both helps protect against and contributes to skin inflammation and sensitization.
research Innate immunity and the regulation and mobilization of keratinocyte stem cells: are the old players playing a new game?
Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.
research An outline of SARS-CoV-2 pathogenesis and the complement cascade of immune system
Understanding SARS-CoV-2's spread and immune response is key to developing treatments and vaccines, but preventive measures remain important.
research 498 Innate immunity activation of sebocyte cells by living bacteria. Evidence of a potential immunosuppressive effect of DHT
DHT may reduce inflammation caused by certain bacteria in skin cells.
research Editorial: Crosstalk: skin cells and immune cells in inflammatory skin diseases
Targeting specific biomarkers and immune signals is more effective and safer for treating inflammatory skin diseases.
research The X Factor in Immunity: Sex Differences Shaped by the X Chromosome
Females generally have stronger immune responses than males due to the X chromosome.
research New developments in our understanding of acne pathogenesis and treatment
We now understand more about what causes acne and this could lead to better, more personalized treatments.
research Immunological aspects of psychodermatology
The skin plays a key role in immune responses and reflects emotional and stress reactions.
research PRF Lysates Modulate Chemokine Expression in Oral Squamous Carcinoma and Healthy Epithelial Cells
PRF lysates reduce inflammation in cancer cells and boost immune response in healthy oral cells.
research Unraveling the web of defense: the crucial role of polysaccharides in immunity
Polysaccharides boost immunity and could help prevent and treat diseases.
research Intestinal Intraepithelial Lymphocytes: Sentinels of the Mucosal Barrier
Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.
research The three acnes and their impact
Isotretinoin effectively treats acne, often providing lasting relief.
research Live Imaging of the Skin Immune Responses
Live imaging helps us understand skin immune responses and develop treatments.
research RNase L represses hair follicle regeneration through altered innate immune signaling
RNase L hinders hair follicle regeneration by altering immune signals.
research Sparse haplotype-based fine-scale local ancestry inference at scale reveals recent selection on immune responses
Recent selection on immune response genes was identified across seven ethnicities.
research Beneficial effects of finasteride on hepatic and pulmonary immune response after trauma hemorrhage in mice
Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.
research What’s Sex Got to Do With COVID-19? Gender-Based Differences in the Host Immune Response to Coronaviruses
Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
research Peripheral MC1R Activation Modulates Immune Responses and is Neuroprotective in a Mouse Model of Parkinson’s Disease
NDP-MSH protects brain cells and reduces inflammation in Parkinson's disease by activating MC1R and involving Tregs.
research Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing
A humanized CXCL12 antibody may delay and treat alopecia areata by altering the immune response.
research PINK1 deficiency rewires early immune responses in a mouse model of Parkinson’s disease triggered by intestinal infection
PINK1 is important for controlling gut immune responses linked to early Parkinson's disease.