4 citations
,
January 2013 in “PubMed” Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.
August 2013 in “Fertility and sterility” Metformin can help diagnose and treat high testosterone levels in women, often due to insulin resistance rather than a tumor.
11 citations
,
August 2020 in “Diabetes” Testosterone helps human pancreatic cells increase insulin release.
Testosterone in human pancreas cells boosts insulin production.
Testosterone in our bodies helps increase insulin secretion from the pancreas.
January 2010 in “Ciencia UANL” Young men with hair loss may have a higher risk of insulin resistance and related health issues.
135 citations
,
March 1984 in “Fertility and sterility” Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.
43 citations
,
May 1988 in “British Journal of Dermatology” Patients with acanthosis nigricans often have insulin resistance and signs of increased male hormones, but treatment targeting these male hormones is generally ineffective.
39 citations
,
August 2001 in “Clinical endocrinology” Lean and obese women with PCOS have similar levels of insulin resistance, indicating it's a core aspect of the condition.
31 citations
,
January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
26 citations
,
January 2000 in “Hormone research in paediatrics” Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.
14 citations
,
January 2008 in “Gynecological Endocrinology” High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.
12 citations
,
January 2016 in “Endocrinology, diabetes & metabolism case reports” Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.
11 citations
,
September 2012 in “Journal of obstetrics and gynaecology Canada” Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.
6 citations
,
May 2016 in “Urolithiasis” Balding and low testosterone increase risk of urinary stones.
1 citations
,
October 2020 in “PubMed” Hormone testing may not be very helpful in diagnosing female pattern hair loss.
November 2025 in “BMC Endocrine Disorders” The TT/DHT ratio may help identify PCOS patients with severe metabolic issues.
August 2024 in “Archives of Women s Mental Health” Women with PCOS have more depression and stress due to high androgen levels, not obesity or insulin resistance.
October 2023 in “ANNALS OF PAKISTAN MEDICAL & ALLIED PROFESSIONALS” Insulin resistance is strongly linked to higher androgen levels in women with PCOS.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Hirsutism and acne indicate high androgen levels in women with PCOS, and early treatment can improve symptoms and quality of life.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Hirsutism and acne indicate high androgen levels in women with PCOS, suggesting early treatment can help.
November 2023 in “JAAD case reports” Exogenous testosterone use may be linked to developing hidradenitis suppurativa.
April 2019 in “Journal of the Endocrine Society” A woman's severe insulin resistance improved with treatment, but she still had high testosterone levels due to ovarian issues.
June 2018 in “Global Journal of Reproductive Medicine” Idiopathic hirsutism may be linked to increased skin enzyme activity, and new treatments like laser and eflornithine cream show promise.
The conclusion is that there's a link between high testosterone levels, insulin resistance, and certain skin conditions, regardless of obesity.
May 2015 in “Endocrine Abstracts” Both finasteride and metformin effectively treat PCOS by reducing hormone levels and insulin resistance.
39 citations
,
September 2000 in “Obstetrics and Gynecology Clinics of North America” Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.
32 citations
,
July 2001 in “Endocrine Practice” Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.
3 citations
,
February 2002 in “The American journal of psychiatry” Stopping birth control pills may have triggered a manic episode in a woman with HAIR-AN syndrome.
2 citations
,
January 2016 in “Journal of Steroids & Hormonal Science” Women with PCOS and polycystic ovaries have higher male hormone levels and more insulin resistance, especially if they are overweight.