research Granules of finasteride and cyclodextrin obtained by hot-melt extrusion to target the hair follicles
Granules improve hair loss treatment by targeting follicles.
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research NF-κB in biology and targeted therapy: new insights and translational implications
NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
research Obstetric Dermatology
The document concludes that managing skin conditions during pregnancy is important and requires specialized care.
research Valproic acid promotes human hair growth in in vitro culture model
Valproic acid may help hair grow and could be a safe treatment for hair loss.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today’s Pre-Clinical Data into Tomorrow’s Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
research The Hair Follicle as an Estrogen Target and Source
Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
research A Novel Point Mutation in the Ligand-Binding Domain (LBD) of the Human Glucocorticoid Receptor (hGR) Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus of hGR LBD in Conferring Transactivational Activity
A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.
research Peroxisome proliferator-activated receptors (PPARs) and PPAR agonists: the ‘future’ in dermatology therapeutics?
PPAR agonists show promise for skin conditions but need more research before being a main treatment.
research Hair Growth Stimulation Effect of Centipeda minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways
Centipeda minima extract helps hair grow by activating important growth signals and could be a promising hair loss treatment.
research Perspectives in dermatopathology: telomeres and telomerase in ageing and cancer; with emphasis on cutaneous disease
Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.
research Exploring caspase functions in mouse models
Caspases affect many cell functions and could help treat various diseases.
research Light emitting diodes technology-based photobiomodulation therapy (PBMT) for dermatology and aesthetics: Recent applications, challenges, and perspectives
LED light therapy is effective for skin and hair treatments but requires careful use to minimize risks.
research Multimodal imaging of hair follicle bulge-derived stem cells in a mouse model of traumatic brain injury
Hair follicle stem cells might help treat traumatic brain injury.
research Maternal androgen excess inhibits fetal cardiomyocytes proliferation through RB-mediated cell cycle arrest and induces cardiac hypertrophy in adulthood
Excess maternal androgens can cause heart problems in offspring.
research A symphony of signals: the intricate role of lncRNAs in dermatological disorders
lncRNAs are important for understanding and treating skin diseases.
research Abstracts of 42nd National Conference of Association of Clinical Biochemists of India (ACBICON 2015)
The conference presented findings on how vitamin D levels, genetic factors, and lifestyle choices like smoking and yoga affect various health conditions and diseases.
research Human pluripotent stem cell-derived skin organoids enabled pathophysiological model of Mycobacterium tuberculosis infection
Skin organoids can model tuberculosis infection and help test treatments.
research Cutaneous lupus erythematosus: a review
Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.
research Hormonal regulation of hair follicles exhibits a biological paradox
Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
research Nanozymes expanding the boundaries of biocatalysis
Nanozymes greatly improve biocatalysis by being stable, efficient, and versatile.
research The prostamide‐related glaucoma therapy, bimatoprost, offers a novel approach for treating scalp alopecias
Bimatoprost, a glaucoma medication, may also help treat hair loss.
research Reconstitution of full-thickness skin by microcolumn grafting
Microcolumn grafting can effectively regenerate full-thickness, functional skin without scarring.
research Triton modified polyethyleneimine conjugates assembled with growth arrest-specific protein 6 for androgenetic alopecia transdermal gene therapy
The treatment effectively promotes hair regrowth in androgenetic alopecia without causing skin irritation.
research Selective Expression of Calcium-Binding Proteins S100A8 and S100A9 at Distinct Sites of Hair Follicles
S100A8 and S100A9 proteins help form hair shafts during growth.
research Orchestration of tissue‐scale mechanics and fate decisions by polarity signalling
Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.
research Cell-free therapy using exosomes: Advancements in the field of dermatology and cosmetology
Exosomes show promise in improving skin health and appearance.
research Upcycling waste hair and feathers derived keratin into intact cortical cell-derived micro-units via periodate oxidation: Applications & life cycle assessment
Keratin from waste hair and feathers can be sustainably used to create stable emulsions for industrial applications.
research TCF/Lef1-Mediated Control of Lipid Metabolism Regulates Skin Barrier Function
TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.
research Extracellular Vesicles in Osteogenesis: A Comprehensive Review of Mechanisms and Therapeutic Potential for Bone Regeneration
Extracellular vesicles can help regenerate bones but need more research for safe clinical use.
research The acyl-CoA binding protein is required for normal epidermal barrier function in mice
ACBP is crucial for healthy skin in mice.