research From molecular biology to therapeutics
The document discusses various skin disorders and new therapeutic approaches.
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300-330 / 1000+ resultsresearch Key Factors in the Complex and Coordinated Network of Skin Keratinization: Their Significance and Involvement in Common Skin Conditions
Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.
research Modern рerspectives on еtiopathogenesis of аlopecia аreata and рromising treatment аpproaches (Review)
Alopecia areata may be treated by targeting immune system imbalances.
research The Human Sebocyte Culture Model Provides New Insights into Development and Management of Seborrhoea and Acne
The human sebocyte culture model has improved understanding of oily skin and acne, and how they can be treated.
research Animal Models of Psoriasis – What Can We Learn from Them?
Rodent models helped understand psoriasis but none perfectly replicated the disease.
research Chemotherapy-Induced Alopecia
Imuvert can prevent some chemotherapy-induced hair loss.
research Allopregnanolone and Induction of Endogenous Opioid Inhibition of Oxytocin Responses to Immune Stress in Pregnant Rats
Allopregnanolone helps control oxytocin levels during pregnancy to prevent preterm labor.
research Acne and hidradenitis suppurativa
Acne and hidradenitis suppurativa have different causes and risk factors, but both are driven by inflammation and may benefit from treatments targeting interleukin-1.
research Pathogenetic Characteristics of Mesenchymal Stem Cells in Hidradenitis Suppurativa
Mesenchymal stem cells in people with Hidradenitis Suppurativa are more inflammatory, possibly contributing to the disease.
research Skin toxicity caused by EGFR antagonists—An autoinflammatory condition triggered by deregulated IL‐1 signaling?
Blocking EGFR can cause skin inflammation by disrupting IL-1 signaling.
research 1 The regulatory biology of the human pilosebaceous unit
Scientists now better understand how human hair growth is controlled, including the roles of specific genes and proteins.
research Distinct use of super-enhancer elements controls cell type–specific CD25 transcription and function
Super-enhancers control CD25 expression in specific cell types, affecting immune function.
research Recalcitrant lichen planopilaris and frontal fibrosing alopecia responding to tildrakizumab
Tildrakizumab significantly improved recalcitrant lichen planopilaris and frontal fibrosing alopecia.
research Epidermal growth factor receptor/mitogen-activated kinase inhibitor treatment induces a distinct inflammatory hair follicle response that includes collapse of immune privilege
EGFRi/MEKi treatments cause hair follicles to lose some immune protection, leading to inflammation.
research Mechanisms of magnesium oxide‐incorporated electrospun membrane modulating inflammation and accelerating wound healing
Magnesium oxide-infused membranes help heal wounds faster by reducing inflammation and promoting skin and hair follicle growth.
research Anti-inflammatory and immunomodulating properties of the herbal preparation indicated for prevention and treatment of alopecia
The herbal preparation may help manage alopecia by reducing inflammation and boosting the immune response.
research Human Placenta Extract (HPH) Suppresses Inflammatory Responses in TNF-α/IFN-γ-Stimulated HaCaT Cells and a DNCB Atopic Dermatitis (AD)-Like Mouse Model
Human placenta extract reduces inflammation and symptoms in atopic dermatitis.
research The immunopathogenesis of Alopecia Areata
Alopecia areata is an autoimmune disease causing hair loss, and targeting macrophages may help treat it.
research A ‘hot’ new twist to hair biology – involvement of vanilloid receptor‐1 signaling in human hair growth control
VR1 signaling can inhibit hair growth by affecting cell processes and increasing hair growth inhibitors.
research Zhuangyao Jianshen pill ameliorates testosterone-induced benign postatic hyperplasia in rats.
Zhuangyao Jianshen pill reduces prostate enlargement and inflammation in rats.
research Medication-induced hair loss: An update
COVID-19 vaccines have been linked to an increase in hair loss conditions.
research CD4 T cells from mice with alopecia areata express an effector like phenotype and can transfer disease
CD4 T cells can cause alopecia areata by activating CD8 T cells to attack hair follicles.
research Alopecia Areata: An Overview of the Disease and its Genetic Basis: Review Article
Understanding the genetics of alopecia areata could lead to better treatments.
research Different levels of EGF, VEGF, IL‐6, MCP‐1, MCP‐3, IP‐10, Eotaxin and MIP‐1α in the adipose‐derived stem cell secretome in androgenetic alopecia
Certain proteins are found at higher levels in balding areas compared to non-balding areas, suggesting a link to hair loss. This could be useful for diagnosing and treating hair loss.
research Local IL-17 orchestrates skin aging
Blocking IL-17 signaling can delay skin aging and improve skin and hair health.
research A Comparative Study to Test a Plant Extract against Minoxidil in HaCaT Cells
The plant extract and minoxidil both reduce hair loss by lowering specific gene expressions.
research Investigation of the Gene Expression Levels of 5 α-reductase, VEGF and IL-1α in HaCaT Cells after the Application of a Botanical Extract
The plant extract may help prevent hair loss by reducing inflammation and promoting hair growth.
research Distribution of human B-defensin 2, TNF-alpha, IL-1 alpha, IL-6 and IL-8 in psoriatic skin
Certain proteins and cytokines are key in causing psoriatic skin issues.
research A biomarker-guided therapeutic map for alopecia: in vivo evidence and clinical implications.
A biomarker-guided approach can improve alopecia treatment by targeting specific pathways.
research Myrtus communis Leaf Extract Modulates IL-1α and VEGF Gene Expressions in HaCaT Cells: Probable Implications for Its Beneficial Effects in Hair Loss and Wound Healing
Myrtus communis leaf extract may help with hair loss and wound healing.