research Small Molecule Inhibitors and Inflammatory Skin Diseases
New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.
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research Disorders of the skin appendages
The document concludes that proper recognition and treatment of skin appendage disorders are important for management.
research Collagen Increasing and Hair Growth Effect of Supramolecular Cosmetic Materials Containing Phytochemicals
The cream with plant components increased skin collagen and the hair tonic promoted hair growth in mice.
research Principles of Therapy of Skin Diseases
Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.
research A national ethics committee
Taking calcium may help elderly with osteoporosis, birth control with levonorgestrel doesn't increase heart attack risk, Salmonella can cause arthritis, a national ethics committee is recommended, and sulfasalazine might help with a hair loss condition.
research 48853 The AI Doctor will see you now: Can ChatGPT-4 be used to safely counsel patients with allergic contact dermatitis?
ChatGPT-4 can help with allergic contact dermatitis but shouldn't replace expert doctors.
research Contact Dermatitis Caused by Topical Minoxidil: Case Reports and Review of the Literature
Minoxidil can cause allergic skin reactions, especially in long-term users.
research Patch Testing in Allergic Contact Dermatitis from Minoxidil
Patch testing helps find allergens in minoxidil treatments, but doesn't ensure alternatives will be tolerated.
research Contact Dermatitis Caused by Topical Minoxidil: Case Reports and Review of the Literature
Minoxidil can cause skin reactions, so testing is important for those with side effects.
research Which is the ideal JAK inhibitor for alopecia areata – Baricitinib, tofacitinib, ritlecitinib or ifidancitinib - Revisiting the immunomechanisms of the JAK pathway
No single ideal JAK inhibitor for alopecia areata has been determined; JAK3 inhibitors may be promising with fewer side effects.
research The Intermediate Filament Architecture as Determined by X-Ray Diffraction Modeling of Hard α-Keratin
Hard α-keratin in hair has a unique, nonordered structure, different from other fibers.
research Recent advances in understanding of radiation-induced skin tissue reactions with respect to acute tissue injury and late adverse effect
Understanding skin reactions to radiation has improved, helping to reduce injuries and prevent skin cancer.
research Hair follicle immune privilege and its collapse in alopecia areata
Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
research Activation of Nrf2 in keratinocytes causes chloracne (MADISH)‐like skin disease in mice
Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
research Mechanistic target of rapamycin (mTOR) expression is increased in acne patients' skin
Acne patients have higher levels of mTOR in their skin, which could be linked to future metabolic disease.
research Targeting the Complexity of In Vitro Skin Models: A Review of Cutting-Edge Developments
In vitro skin models are improving but still need more innovation to fully replicate human skin.
research Evaluation of utility of phenol in alopecia areata
88% phenol is effective for treating alopecia areata.
research A novel cell-penetrating peptide supports hair follicle growth through anti-inflammatory and growth factor–associated mechanisms in preclinical models
A new peptide, DualPep-ALO, may help hair growth by reducing inflammation and boosting growth factors.
research Wnt signaling modulates mechanotransduction in the epidermis to drive hair follicle regeneration
Wnt signaling helps regenerate hair follicles by affecting how skin cells sense and respond to mechanical forces.
research Clinical study of common bacterial, fungal and parasitic skin diseases in cats
Fungal infections are the most common skin disease in cats, especially white ones.
research Features Associated With Quality of Life Impairment in Hidradenitis Suppurativa Patients
Hidradenitis suppurativa severely impacts quality of life, especially with severe symptoms and certain comorbidities, and current treatments don't significantly improve it.
research Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles
ASC-CM is more effective than EV for treating osteoarthritis.
research Combined effect of high-dose vitamin A, vitamin E supplementation, and zinc on adult patients with diabetes: A randomized trial
High-dose vitamin A and E with zinc improved blood sugar control and insulin function in diabetics, but may cause hair loss.
research The application of local hypobaric pressure — A novel means to enhance macromolecule entry into the skin
Local hypobaric pressure can significantly improve drug delivery through the skin.
research Ex Vivo Assessment of Heat and Humidity Effects on Human Skin and Potential Protection by Kombucha Tea Extract
Kombucha tea extract may protect skin from damage in hot and humid conditions.
research Quantifying whole human hair scalp fibres of varying curl: A micro‐computed tomographic study
Human hair varies in structure based on curl type, with high curl hair showing the most differences.
research Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice
Dermal adipose tissue in mice can change and revert to help with skin health.
research Deimination and Peptidylarginine Deiminases in Skin Physiology and Diseases
PADs are crucial for healthy skin and hair, and their imbalance can cause skin and hair disorders.
research Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases
research Effects of microenvironment and biological behavior on the paracrine function of stem cells
Mesenchymal stem cells release substances that help tissue repair, and their effectiveness can be improved by understanding environmental influences.