July 2025 in “Cell & Bioscience” Specific immune cells and pathways contribute to hair follicle inflammation and hair loss, suggesting potential treatments for lichen planopilaris.
Exosome therapies improve skin, hair, and healing but face challenges like cost and regulation.
49 citations
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November 2021 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
46 citations
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August 2022 in “Animals” miR-144-y and FOXO3 play key roles in skin and feather development in Zhedong White geese.
September 2025 in “PubMed” Mechanical stimulation and new therapies show promise for hair regrowth.
January 2025 in “Research” Cellular senescence can both hinder and promote hair growth, suggesting new ways to treat hair loss.
79 citations
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January 2002 in “Nucleic Acids Research” BMP-2 activates the Dlx3 gene in mouse skin cells, important for hair and skin development.
21 citations
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September 2010 in “Cancer Prevention Research” Overactive signaling in hair follicles can lead to skin cancer.
9 citations
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November 2020 in “The FASEB journal” Intermediate filaments are crucial for cell differentiation and stem cell function.
1 citations
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October 2025 in “International Journal of Molecular Sciences” Mutating the gmds gene in zebrafish increases hair cell numbers and regeneration.
1 citations
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July 2025 in “Frontiers in Veterinary Science” Tibetan sheep have specific genes for high-altitude adaptation and wool traits, aiding breeding strategies.
December 2025 in “Molecules” DPP may help hair regrowth by improving blood vessel function under stress.
December 2023 in “European Journal of Medicinal Chemistry” Natural products might be safe, effective, and affordable treatments for hair loss.
75 citations
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July 2016 in “New phytologist” The protein RSL4 is crucial for making root hairs longer by controlling genes related to cell growth.
15 citations
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July 2015 in “Developmental Dynamics” Orai1 protein is crucial for tooth development and affects enamel thickness and mineralization.
April 2023 in “Journal of Investigative Dermatology” Exosomes from certain stem cells can fight hair loss by promoting hair growth and maintaining the growth phase of hair.
418 citations
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January 2018 in “Journal of Investigative Dermatology” Researchers found four distinct fibroblast types in human skin, which could help in treating wounds and fibrotic diseases.
July 2025 in “ACS Pharmacology & Translational Science” Maslinic acid from olive extracts promotes hair growth like minoxidil.
26 citations
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September 2012 in “Cell Reports” B-Raf and C-Raf are essential for maintaining melanocyte stem cells to prevent hair graying.
20 citations
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February 2023 in “Biology” Innovative cosmetics could safely change hair color by targeting biological hair pigmentation processes.
10 citations
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January 2013 in “Regenerative Medicine Research” Rejuvenating self-repair mechanisms could improve organ recovery in regenerative medicine.
176 citations
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February 2006 in “Cancer Research” Patched1 helps prevent tumors by controlling cell growth.
137 citations
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January 2006 in “Frontiers in bioscience” CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
62 citations
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March 2017 in “Journal of Investigative Dermatology” Mutations in the ACTB gene cause Becker’s nevi and may lead to muscle issues in Becker’s nevus syndrome.
11 citations
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February 2018 in “Oncotarget” Lower SMAD2/3 activation predicts more severe skin cancer.
8 citations
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February 2025 in “Pharmaceuticals” Polyphenols may help treat skin diseases due to their anti-inflammatory and antioxidant effects.
1 citations
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August 2025 in “International Journal of Molecular Sciences” Nutraceutical insulin-sensitizing agents may help treat skin conditions like psoriasis and acne.
1 citations
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May 2025 in “Current Issues in Molecular Biology” Centipeda minima and brevilin A protect skin cells from damage and aging.
Pvalb8 is essential for zebrafish hearing and hair cell development, and its mutation causes hearing loss.
September 2025 in “Biomolecules” The skin microenvironment significantly affects hair growth and loss, offering potential treatment avenues.