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research In Vitro and In Vivo Scalp Retention and Penetration of 99mTc-Minoxidil Solution
Thicker minoxidil solutions work better and need less frequent application.
research Elevated Circulation Levels of an Antiangiogenic SERPIN in Patients with Diabetic Microvascular Complications Impair Wound Healing through Suppression of Wnt Signaling
High kallistatin levels in diabetics worsen wound healing by blocking important cell signals.
research 582 The Patent Landscape Analysis of Skin Bioinks for 3D Bioprinting
3D skin bioprinting, using skin bioinks like collagen and gelatin, is growing fast and could help treat wounds, burns, and skin cancers, as well as test cosmetics and drugs.
research Transient skin stretching stimulates immune surveillance and promotes vaccine delivery via hair follicles
Skin stretching can improve vaccine delivery through hair follicles and boost immune response.
research Influence of Liposomes and Niosomes on the In Vitro Permeation and Skin Retention of Finasteride
Liposomes and niosomes can increase finasteride retention in the skin.
research Sunscreen remanence on the skin: a noninvasive real time in vivo spectral analysis assessing the quenching of specular ultraviolet A light reflectance
Sunscreens with UVA blockers effectively reduce skin fluorescence for several hours.
research Fast clinical response with topical ruxolitinib in the management of non-segmental vitiligo detected by VISIA® analysis system
Topical ruxolitinib quickly improves non-segmental vitiligo.
research A microfluidic application for mass production of drug-loaded polymeric microspheres for a long-acting injectable with IVL-DrugFluidic®, a novel microfluidic microsphere manufacturing platform technology
IVL-DrugFluidic® can mass-produce high-quality, long-acting injectable drug microspheres, improving patient compliance and reducing side effects.
research Dexmedetomidine-Loaded Hydrogel Microneedles Alleviate Acute Inflammatory Visceral Pain in Mice
The study introduces a novel approach for treating acute inflammatory visceral pain (AIVP) using dexmedetomidine-loaded hyaluronic acid hydrogel microneedles (MN/Dex). This method offers a minimally invasive, patient-friendly alternative to traditional intravenous administration, which can be uncomfortable and pose infection risks. The microneedles enable efficient skin penetration and controlled drug release, demonstrating excellent biocompatibility in biosafety evaluations. In a mouse model of AIVP, MN/Dex significantly reduced pain without causing sedation or affecting normal behaviors, suggesting its potential to improve outpatient management and quality of life for patients with AIVP.
research Multiphoton microscopic imaging of in vivo hair mouse skin based on two‐photon excited fluorescence and second harmonic generation
Multiphoton microscopy effectively images mouse skin layers and structures.
research Efficacy of intralesional corticosteroid injections for scalp vitiligo: An effective therapeutic option
Intralesional corticosteroid injections effectively treat scalp vitiligo.
research In Vitro Percutaneous Permeation and Skin Accumulation of Finasteride Using Vesicular Ethosomal Carriers
Ethosomes improve finasteride delivery through skin for hair loss treatment.
research Injectables for Hair Loss Treatment
research Mechanical Instability of Adherens Junctions Overrides Intrinsic Quiescence of Hair Follicle Stem Cells
Weak cell junctions disrupt hair follicle stem cell rest.
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/research/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs
ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
research A double-blind, placebo-controlled study with Kevis lotion
research Kerion Celsi favored by the use of a tretinoin+minoxidil+betamethasone valerate lotion in a 28-year-old woman.
A lotion with tretinoin, minoxidil, and betamethasone valerate helped treat a woman's skin infection.
research On the Use of Micro-Imager® to Directly Visualize Drug Distribution in Human Skin
Micro-Imager® helps see how drugs spread in human skin.
research Intravital imaging of host–parasite interactions in skin and adipose tissues
Intravital microscopy helps us see how parasites interact with skin and fat in living animals.
research Comparing Traditional and “In-Motion” Intense Pulsed Light Techniques for Hair Removal: A Split Study
The "in-motion" technique for hair removal is less painful and safer than the traditional method, with similar effectiveness.
research Novel Vegan Exosome-like Biomimetic Vesicles for Skin and Hair Follicle Protection and Rejuvenation: Structural and Functional Characterization and Placebo-Controlled Clinical Efficacy Studies
Vegan exosome-like vesicles from microalgae improve skin and hair health, reducing wrinkles and enhancing elasticity.
research 1339 Casein kinase 1 inhibition in keratinocytes enhances the migration of melanocyte precursors in the hair follicle via KitL/c-Kit signaling pathway
Blocking casein kinase 1 in skin cells can help melanocyte precursors move better, potentially helping with conditions like vitiligo or gray hair.
research Investigation of in vitro and in vivo skin permeability using laser scanning microscopy
Nanoparticles in sunscreen are generally safe as they stay on the skin's surface.
research Sinergia entre ácido hialurónico y luz infrarroja. Estudio preliminar
Infrared light, alone or with hyaluronic acid, effectively treats skin laxity with minimal side effects.
research Treatment of vitiligo with the topical Janus kinase inhibitor ruxolitinib: A 32-week open-label extension study with optional narrow-band ultraviolet B
research 569 Application of 3D scaffold free dermal spheroids to investigate retinol and retinol alternatives mechanism of action on extracellular matrix
research Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1
Vitexin Compound 1 may help reduce skin aging caused by UVA light.
research Sustained release of inhibitor from bionic scaffolds for wound healing and functional regeneration
Researchers developed a scaffold that releases a healing drug over time, improving wound healing and skin regeneration.
research Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis
Loss of a specific protein in skin cells causes symptoms similar to psoriasis.