Search

for
Search:

Sort by

Research

570-600 / 1000+ results

research Gene Array Profiling and Immunomodulation Studies Define a Cell-Mediated Immune Response Underlying the Pathogenesis of Alopecia Areata in a Mouse Model and Humans

114 citations , August 2002 in “Journal of Investigative Dermatology”

Alopecia areata is caused by an immune response, and targeting immune cells might help treat it.

research The Auxin-Regulated CrRLK1L Kinase ERULUS Controls Cell Wall Composition during Root Hair Tip Growth

109 citations , February 2018 in “CB/Current biology”

ERULUS controls root hair growth by regulating cell wall composition and pectin activity.

research Human Wharton’s Jelly Mesenchymal Stem Cells Plasticity Augments Scar-Free Skin Wound Healing with Hair Growth

102 citations , April 2014 in “PloS one”

Wharton’s Jelly stem cells from the umbilical cord improve skin healing and hair growth without scarring.

research Epidermal Vascular Endothelial Growth Factor Production Is Required for Permeability Barrier Homeostasis, Dermal Angiogenesis, and the Development of Epidermal Hyperplasia

100 citations , August 2008 in “American Journal Of Pathology”

VEGF-A is crucial for normal skin function and may be linked to psoriasis.

research Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation

90 citations , July 2020 in “Stem Cell Research & Therapy”

Stem cell vesicles can reduce skin aging from UVB by lowering inflammation and oxidative stress.

research Changing Patterns of Localization of Putative Stem Cells in Developing Human Hair Follicles

87 citations , February 2000 in “Journal of Investigative Dermatology”

Stem cells in developing hair follicles move to specific areas as they mature.

research Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt

83 citations , October 2012 in “International Journal of Oncology”

Wedelolactone selectively kills prostate cancer cells without harming normal cells.

research LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem‐Like Cells

82 citations , July 2012 in “Brain pathology”

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

research Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells

80 citations , June 2002 in “Molecular Biology of the Cell”

Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.

research Fabrication of Bilayer Nanofibrous-Hydrogel Scaffold from Bacterial Cellulose, PVA, and Gelatin as Advanced Dressing for Wound Healing and Soft Tissue Engineering

78 citations , February 2024 in “ACS Omega”

The scaffold is a promising material for wound healing and tissue engineering.

research Role of the Notch Ligand Delta1 in Embryonic and Adult Mouse Epidermis

78 citations , October 2007 in “Journal of Investigative Dermatology”

Delta1 is crucial for controlling skin cell growth and preventing tumors in mice.

research Transient CD44 Variant Isoform Expression and Reduction in CD4+/CD25+ Regulatory T Cells in C3H/HeJ Mice with Alopecia Areata

77 citations , June 2002 in “Journal of Investigative Dermatology”

CD44 variant changes start alopecia areata, but don't maintain it.

research A Transition State Analogue of 5′-Methylthioadenosine Phosphorylase Induces Apoptosis in Head and Neck Cancers

75 citations , June 2007 in “Journal of Biological Chemistry”

MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.

research Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930

65 citations , February 2011 in “Molecular cancer therapeutics”

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

research Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions

61 citations , July 2011 in “PLOS ONE”

Spermidine may help reduce hair loss and deserves further testing as a treatment.

research Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles

60 citations , December 2020 in “Stem Cell Research & Therapy”

ASC-CM is more effective than EV for treating osteoarthritis.

research Hydroxyl radical mediates cisplatin-induced apoptosis in human hair follicle dermal papilla cells and keratinocytes through Bcl-2-dependent mechanism

52 citations , May 2011 in “APOPTOSIS”

Hydroxyl radicals cause hair follicle cell death during chemotherapy by reducing Bcl-2 protein levels.

research Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells

51 citations , October 2019 in “Cells”

Baricitinib reduces inflammation and improves cell health in premature aging cells.

research SARS-CoV-2 Spike Protein S1-Mediated Endothelial Injury and Pro-Inflammatory State Is Amplified by Dihydrotestosterone and Prevented by Mineralocorticoid Antagonism

50 citations , November 2021 in “Viruses”

Spironolactone may help reduce COVID-19 severity in men by blocking harmful effects of certain hormones.

research Alcoholic Extract of Eclipta alba Shows In Vitro Antioxidant and Anticancer Activity without Exhibiting Toxicological Effects

49 citations , January 2017 in “Oxidative Medicine and Cellular Longevity”

Eclipta alba extract may help fight cancer and has antioxidant benefits without being toxic.

research The Comparison of In Vitro Photosensitizing Efficacy of Curcumin-Loaded Liposomes Following Photodynamic Therapy on Melanoma MUG-Mel2, Squamous Cell Carcinoma SCC-25, and Normal Keratinocyte HaCaT Cells

48 citations , April 2021 in “Pharmaceuticals”

Liposomal curcumin improves skin cancer treatment effectiveness while sparing normal cells.

research Hollow polydopamine nanoparticles loading with peptide RL-QN15: a new pro-regenerative therapeutic agent for skin wounds

47 citations , October 2021 in “Journal of Nanobiotechnology”

HPDAlR nanoparticles greatly improve skin wound healing without toxicity.

research Existence of Neural Crest–Derived Progenitor Cells in Normal and Fuchs Endothelial Dystrophy Corneal Endothelium

44 citations , September 2016 in “American Journal Of Pathology”

Neural crest-derived progenitor cells in the cornea could help treat corneal issues without transplants.

research Paclitaxel-loaded star-shaped copolymer nanoparticles for enhanced malignant melanoma chemotherapy against multidrug resistance

43 citations , March 2017 in “Drug Design Development and Therapy”

The new nanoparticles could improve melanoma treatment by working better than current options.

research Combinatorial Therapy of Letrozole- and Quercetin-Loaded Spanlastics for Enhanced Cytotoxicity against MCF-7 Breast Cancer Cells

39 citations , August 2022 in “Pharmaceutics”

Combining letrozole and quercetin in spanlastics may improve breast cancer treatment.

research A temperature-sensitive FERONIA mutant allele that alters root hair growth

37 citations , December 2020 in “PLANT PHYSIOLOGY”

A mutant FERONIA gene affects root hair growth at high temperatures.

research AtCSLD3 and GhCSLD3 mediate root growth and cell elongation downstream of the ethylene response pathway in Arabidopsis

35 citations , December 2017 in “Journal of Experimental Botany”

AtCSLD3 and GhCSLD3 genes enhance root growth and cell elongation in plants.

← Previous page Next page →