5 citations
,
July 2022 in “Orphanet journal of rare diseases” RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
344 citations
,
June 2006 in “American Journal Of Pathology” Human hair follicles can provide stem cells for regenerative medicine.
233 citations
,
October 2004 in “Differentiation” Stem cells are in deep skin layers, while differentiating cells are in shallow layers.
1 citations
,
November 2024 in “Cureus” Recognizing RSCC is crucial due to its aggressive nature and high risk of poor outcomes.
2 citations
,
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Neural stem cells use local feedback to maintain balance in the adult brain.
August 2023 in “Cell Proliferation” Human cells in plasma-derived gels can potentially mimic hair follicle environments, improving hair regeneration therapies.
The review suggested the study needed to clarify its purpose, compare with non-immortalized cells, and provide more details on methods.
June 2019 in “International journal of dermatology and venereology” The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.
November 2025 in “Bioengineering” The new method may improve skin grafts and hair growth.
45 citations
,
January 2021 in “Stem Cell Research & Therapy” The combination of stem cell medium and hydrogel effectively reduces and improves hypertrophic scars.
27 citations
,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Somatostatin may help protect hair follicles from immune attacks.
15 citations
,
November 2020 in “Development” Stem cells in the eye have different roles and behaviors, helping maintain and repair the eye's surface.
44 citations
,
October 2017 in “Scientific Reports” Far-infrared radiation improves stem cell growth and movement, helping heart therapy.
12 citations
,
April 2022 in “Journal of Bioscience and Bioengineering” Activating the PI3K/Akt pathway improves hair growth by human dermal papilla cells in hair beads.
9 citations
,
July 2007 in “Circulation Research” Defects in certain proteins cause major heart abnormalities during early development.
11 citations
,
April 1993 in “PubMed” Human hair cells can change based on their environment, especially interactions with certain skin cells.
18 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
40 citations
,
March 2019 in “Nature Communications” CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
1 citations
,
October 2025 in “Nature Communications” Cell size controls when stem cells divide.
29 citations
,
February 2001 in “Proceedings of the National Academy of Sciences” A specific DNA region controls skin cell gene expression by working with certain proteins.
October 2018 in “Current Opinion in Genetics & Development” The document emphasizes the importance of ongoing research and ethical considerations in genome editing and cellular reprogramming.
A low dose of rapamycin increases inner ear hair cell creation by boosting SOX2+ cell numbers.
1 citations
,
October 2021 in “Journal of Investigative Dermatology”
April 2017 in “Plastic and reconstructive surgery. Global open” Fetal scalp cells have more regenerative genes than adult cells, and decellularized muscle matrix is better for muscle repair than commercial alternatives.
December 2021 in “Morphologia” Neural crest cells could be used in regenerative medicine due to their ability to become different cell types.
5 citations
,
January 2005 in “Cytotherapy” The meeting highlighted important advances in stem cell research and its potential for creating new medical treatments.
137 citations
,
April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
1 citations
,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
28 citations
,
December 2018 in “Plant, cell & environment/Plant, cell and environment” A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.
15 citations
,
February 2021 in “Scientific Reports” A specific group of stem cells can help regenerate hair continuously.