research Rivaroxaban-induced hair loss
Rivaroxaban may cause hair loss.
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research Lisinopril-Induced Alopecia: A Case Report
Lisinopril, a heart medication, probably caused hair loss in a patient, which stopped after switching drugs.
research Effect of adenosine triphosphate on ribociclib-induced skin toxicity in rats
research Antihypertensive Agents in Dermatology
research Reversible ageusia associated with losartan
Losartan can cause temporary loss of taste.
research PC-SPES Studies Promising, But Manufacturer Shuts Down
Promising cancer treatments were found, but the manufacturer closed.
research Effect of minoxidil on blood pressure and hemodynamics in severe hypertension
research Real-world safety of ixekizumab: a disproportionality analysis using the FDA adverse event reporting system and the VigiAccess databases
Ixekizumab has known and some unexpected side effects.
research Polyphenols rich Hibiscus rosa sinensis Linn. petals modulate diabetic stress signalling pathways in streptozotocin-induced experimental diabetic rats
Hibiscus petals improved blood sugar and stress responses in diabetic rats.
research Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program
Ritlecitinib is safe and well-tolerated for treating alopecia areata in patients aged 12 and older.
research Aldo-Keto Reductase (AKR) 1C3 inhibitors: a patent review
The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
research Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research 5PSQ-056 Experience with tofacinitib and baricitinib in rheumatoid arthritis
Tofacitinib and baricitinib had an acceptable level of side effects in rheumatoid arthritis patients.
research Acute oral toxicity and phytochemistry of Catharanthus roseus and Schwenckia americana used as antidiabetic plants in Southern Benin
Catharanthus roseus and Schwenckia americana extracts are generally safe but may cause kidney and liver tissue damage.
research Significant improvement with ivarmacitinib after suboptimal response to tofacitinib in severe alopecia areata: a case report and literature review
Ivarmacitinib significantly improved hair regrowth in severe alopecia areata after tofacitinib was less effective.
research Differential effects of propranolol on heart rate and plasma renin activity in patients treated with minoxidil
Propranolol affects heart rate and renin levels in minoxidil-treated patients.
research Upadacitinib for management of alopecia areata and rheumatoid arthritis: Letter to the editor
Upadacitinib significantly improved both rheumatoid arthritis and alopecia areata in a patient.
research A perspective on small molecules targeting the renin–angiotensin–aldosterone system and their utility in cardiovascular diseases: exploring the structural insights for rational drug discovery and development
Targeting the RAAS with small molecules can improve cardiovascular disease treatments.
research Flecainide
A man with lung cancer had skin and eye side effects from erlotinib but continued treatment with symptom improvement.
research Minoxidil in severe hypertension: Value when conventional drugs have failed
Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
research Rapid Screening of Anticoagulation Compounds for Biological Target-Associated Adverse Effects Using a Deep-Learning Framework in the Management of Atrial Fibrillation
The framework helps predict adverse effects of blood thinners, improving drug selection for atrial fibrillation.
research Adverse events in patients treated with Jak‐inhibitors for alopecia areata: A systematic review
JAK-inhibitors for alopecia areata are generally safe with mostly mild side effects and a low rate of treatment withdrawal.
research TREATMENT OF REFRACTORY HYPERTENSION
Most patients with hard-to-treat high blood pressure can be managed effectively with various treatments, but no single treatment is perfect.
research Minoxidil treatment in maintenance hemodialysis patients with refractory hypertension
Minoxidil effectively manages severe hypertension in hemodialysis patients with minimal side effects.
research Actos, slings, finasteride, and the vaccine compensation solution.
research Empagliflozin targeting STAT3/Akt/Nrf2 axis promoting diabetic wound healing in rat model
Empagliflozin helps heal diabetic wounds in rats by reducing inflammation and oxidative stress.
research Zizyphus jujubaprotects against ibuprofen-induced nephrotoxicity in rats
Jujube fruit extract may reduce kidney damage from ibuprofen in rats.
research Refractory/relapse thrombocytopenia in a patient with Evans' syndrome successfully treated with zanubrutinib
A girl with Evans' syndrome had her low platelet count successfully treated with zanubrutinib.
research Biotransformation of tirilazad in human: 4. effect of finasteride on tirilazad clearance and reduced metabolite formation.
research Virtual Bioequivalence Assessment of Ritlecitinib Capsules with Incorporation of Observed Clinical Variability Using a Physiologically Based Pharmacokinetic Model
50-mg ritlecitinib capsules are bioequivalent to 100-mg capsules.