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December 2000 in “PubMed” The biology of skin and hair is complex and not fully understood.
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July 2025 in “JCI Insight” Hair follicle stem cells help maintain skin health by moving to and supporting the skin's surface layers.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Using enzymes to break down scalp hair follicles gets more stem cells for skin and hair growth than the old method.
24 citations
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February 2011 in “The American journal of pathology” AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.
July 2024 in “Journal of Investigative Dermatology” CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.
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March 2010 in “Plastic & Reconstructive Surgery” A simple, safe, and cost-effective method using adhesive drapes effectively removes hair from scalp grafts, reducing infection risk.
51 citations
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February 2009 in “Journal of dermatological science” Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.
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April 2016 in “Journal of Visualized Experiments” The method successfully isolates hair follicle stem cells from mice for research.
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March 1995 in “Differentiation” A rabbit gene important for hair development was identified and detailed.
February 2026 in “Trials” The Exfoliate-Dissolve-Repair skincare approach may effectively treat keratosis pilaris and reduce the need for corticosteroids.
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September 1997 in “Developmental Biology” November 2025 in “Journal of Investigative Dermatology” Skin-associated cartilage cells can influence hair growth by altering specific signaling pathways.
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August 1985 in “Archives of dermatology” A lotion helped remove hair casts, which seem to come from a specific part of the hair follicle, and patients with hair casts can be grouped based on the cause.
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November 1960 in “Experimental Biology and Medicine” Hair growth stages don't significantly change lipid content in mouse skin.
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August 1999 in “Journal of Investigative Dermatology” Bikunin is found on the cell boundaries of certain skin layers and may help regulate skin and hair functions.
April 2018 in “Journal of Investigative Dermatology” Ceramide synthase 4 is essential for maintaining skin barrier health.
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April 2012 in “Laser Physics Letters” Antiseptic particles penetrate deeper into hair follicles than non-antiseptic ones.
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January 2014 in “Medical Entomology and Zoology” 40 citations
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July 2019 in “Journal of Investigative Dermatology” Lack of a key enzyme causes severe skin issues and death in mice.
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January 2014 in “Annals of Dermatology” Sfrp2 increases during hair follicle catagen phase and slows keratinocyte growth.
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June 1970 in “Journal of Investigative Dermatology” December 2025 in “Indian Journal of Dermatology” Extraction videodermoscopy is an effective, non-invasive diagnostic tool for eruptive vellus hair cysts.
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June 2022 in “Frontiers in Bioengineering and Biotechnology” The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.
April 2017 in “Journal of Investigative Dermatology” The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.
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June 1993 in “Archives of Dermatological Research”
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January 2012 in “International journal of trichology” The study found that hair fragility in Pili annulati may be caused by cavities and damage within the hair shafts.
December 2025 in “Nature Communications” Club-like receptors detect light touch but not whisking.