17 citations
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September 2016 in “Stem cells translational medicine” Using bioreactors, scientists can grow more skin stem cells that keep their ability to regenerate skin and hair.
March 2025 in “American Journal of Medical Genetics Part A” A rare genetic variant linked to skin cysts was found in blood DNA, suggesting its role in cyst formation.
20 citations
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May 2011 in “Journal of Clinical Investigation” The study created a mouse model to mimic degenerative diseases for testing tissue repair and new therapies.
July 2025 in “Journal of Investigative Dermatology” Scarring alopecia involves increased immune cells and specific gene changes near damaged hair follicles.
24 citations
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February 2015 in “Experimental Cell Research” NFIC helps human dental stem cells grow and become tooth-like cells.
Pygo2 is important for early growth and progression of intestinal tumors, and could be a target for treating cancers with certain mutations.
Clitocybin A can promote hair growth by increasing cell proliferation.
December 2025 in “EMBO Reports” Cells communicate with neighbors to coordinate their development.
37 citations
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January 1986 in “Carcinogenesis” ODC expression in mouse skin and tumors is varied and can be inhibited by retinoic acid or cycloheximide.
November 2022 in “Journal of Investigative Dermatology” The medicine Cyclosporin A might cause excessive hair growth by reducing a protein that controls hair growth.
35 citations
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January 2006 in “Cancer Research” Mice with extra PKCδ resist chemical-induced skin cancer but not UV-induced.
Mdm2 is crucial for controlling p53 to maintain healthy cells and prevent tumors.
April 2018 in “Radiotherapy and Oncology” Prostaglandin helps regenerate hair follicles after radiation damage.
5 citations
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July 2024 in “Journal of Microbiology and Biotechnology” ICP5249 helps hair grow by activating a specific cell pathway.
166 citations
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September 2011 in “The Journal of Cell Biology” p63 controls Satb1 to help skin develop properly.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
March 2014 in “Chinese Journal of Dermatology” Hair loss in androgenic alopecia patients is linked to changes in certain genes that control cell growth and death.
1 citations
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May 2025 in “Cell Reports Medicine” RSPO1 could help create new diabetes treatments by increasing pancreatic β cells.
13 citations
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April 2019 in “iScience” EGFR helps control how hair grows and forms without needing p53 protein.
29 citations
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October 2016 in “Cell death and differentiation” ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.
11 citations
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March 2014 in “Journal of Investigative Dermatology” Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.
April 2017 in “Journal of Investigative Dermatology” Certain compounds can protect hair cells from aging and promote growth.
April 2023 in “Journal of Investigative Dermatology” Cyclosporin A, a drug, reduces TGF-β2 expression in skin cells, potentially causing excessive hair growth through a process involving the calcineurin/NFAT pathway.
87 citations
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July 2018 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
Type XVII collagen helps control skin cell growth and may have anti-aging effects.
123 citations
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November 2012 in “Stem cells” MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.
June 2025 in “Proceedings of the National Academy of Sciences” A PIK3CA mutation in Schwann cells causes severe nerve damage and increased glycolysis, but early treatment can help.
A new compound from Royoporus badius activates immune cells and induces inflammatory responses.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking a key energy pathway in human hair follicles can trigger stress responses that stop cell growth.
November 2025 in “Journal of Investigative Dermatology” PCFCL may have unrecognized subtypes and needs more research.