January 2026 in “Advanced Science” The study explores the role of DDRGK1-mediated ER-phagy in noise-induced hearing loss (NIHL), revealing that ER-phagy is crucial for maintaining ER homeostasis and cell survival. It was found that noise exposure decreases XIAP and DDRGK1 protein levels, inhibiting ER-phagy. XIAP binds to DDRGK1, enhancing its stability and activating ER-phagy. In noise-exposed CBA/CaJ mice, gastrodin, a traditional Chinese medicine ingredient, mitigates cochlear hair cell loss, synaptic damage, and hearing loss by promoting XIAP expression, which increases DDRGK1 levels and activates ER-phagy. These results suggest that targeting XIAP-DDRGK1-mediated ER-phagy could be a novel therapeutic approach for treating NIHL.
11 citations
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June 2016 in “npj Regenerative Medicine” The symposium concluded that understanding how different species repair tissue and how this changes with age can help advance regenerative medicine.
3 citations
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November 2024 in “Clinical Research” Deuruxolitinib is FDA-approved for treating severe alopecia areata.
14 citations
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February 2000 in “Feminism & Psychology” The entry showed that PCOS negatively affects women's self-image and is worsened by societal expectations, suggesting a need for more feminist attention to the condition.
12 citations
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January 2019 in “Regenerative Medicine” The document suggests a need for collaboration, better evidence, and a responsible framework to safely and effectively advance regenerative therapies to clinical use.
10 citations
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September 2023 in “Cureus” Combining platelet-rich plasma and hyaluronic acid effectively reduces pain and improves function in TMJ disorders.
March 2026 in “International Journal of Molecular Sciences” PRP therapy's success varies and depends on PRP quality and patient condition, with athletes benefiting more.
1 citations
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December 2016 JAK inhibitors have therapeutic potential but pose significant risks, requiring careful monitoring.
13 citations
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March 2023 in “Cureus” Transgender individuals face insurance barriers to gender-affirming surgery, needing policy reforms for better access.
March 2019 in “Hair transplant forum international” A malpractice lawsuit was filed over improper delegation in a hair transplant procedure.
November 2003 in “Hair transplant forum international” I'm sorry, but I can't provide a conclusion without the content of the document.
12 citations
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March 2021 in “Patient Preference and Adherence” Patients and oncologists prioritize survival benefits, while payers focus on treatment costs.
January 2019 in “프로그램북(구 초록집)” Both tofacitinib and ruxolitinib are effective and tolerable for treating alopecia areata.
68 citations
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September 2018 in “Trends in Cell Biology” Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.
3 citations
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July 2025 in “Clinical and Experimental Dermatology” Ritlecitinib may be more effective for severe alopecia areata than conventional treatments.
98 citations
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July 2001 in “Journal of Endocrinology” Physicians should promote natural performance improvement and question drug-enhanced achievements.
November 2013 in “International Society of Hair Restoration Surgery” March 2014 in “International Society of Hair Restoration Surgery” June 2024 in “Military Medicine” Access to JAK inhibitors for alopecia areata should be improved in the Military Healthcare System.
January 2025 in “Bright Sky Publications eBooks” Advancements in medical physics and laser technology are improving healthcare but access remains unequal globally.
July 2024 in “Journal of Investigative Dermatology” May 2018 in “International Society of Hair Restoration Surgery” March 2018 in “International Society of Hair Restoration Surgery” January 2018 in “International Society of Hair Restoration Surgery” September 2017 in “International Society of Hair Restoration Surgery” July 2017 in “International Society of Hair Restoration Surgery” May 2017 in “International Society of Hair Restoration Surgery” January 2026 in “SSRN Electronic Journal” January 2026 in “SSRN Electronic Journal” January 2026 in “SSRN Electronic Journal”