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April 2023 in “Frontiers in Pharmacology” ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.
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January 2025 in “Journal of Cosmetic Dermatology” Inhibiting ACE2 improves skin regeneration during tissue expansion.
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January 2025 in “Molecules and Cells” Use ethical and humane practices in mouse research.
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September 2014 in “PLoS ONE” SK2 channels help control sensory signals in rat muscle spindles and hair follicles.
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January 2022 in “Journal of Research in Pharmacy” Cotinus coggygria extract cream may help heal burn wounds.
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November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Gene expression, especially Dkk4, is key to cat color patterns.
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December 2023 in “Medicine” Lower levels of MYLK and CALD1 in bladder cancer and osteosarcoma are linked to worse survival rates.
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October 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Rodent models of PCOS show some similar and some different lipid changes compared to humans.
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November 2023 in “Clinical Pharmacokinetics” Ritlecitinib shows promise as a versatile treatment for various autoimmune and inflammatory diseases.
January 1987 in “Toxicological sciences” SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe symptoms and organ damage in mice.
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February 2018 in “Scientific Reports” Using a drug to activate bone marrow stem cells can help the liver regenerate and function better after major surgery in rats.
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December 2004 in “Neuropharmacology” Progesterone reduces anxiety without needing progesterone receptors.
July 2025 in “Journal of Investigative Dermatology” Discoid lupus erythematosus involves immune activation and fibrosis around hair follicles, with shared pathways across humans, dogs, and mice, suggesting potential treatments for both humans and animals.
March 2021 in “Research Square (Research Square)” Strontium ranelate helps cartilage growth by blocking a specific cell pathway.
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September 2021 in “Cureus” The rs1128977 gene variant may affect cholesterol and body measurements.
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June 2010 in “Bioorganic & medicinal chemistry letters” Two new compounds were found to effectively reduce hair growth in mice.
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August 1998 in “Pain” Blocking GABA(A) receptors increases neuron sensitivity, showing GABA and glycine have different roles in pain.
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October 1988 in “Clinics in Dermatology” Scientists identified and cloned specific keratin proteins in mouse hair.
Ocu-miR-205 affects hair density in Rex rabbits by promoting cell changes and influencing hair follicle phases.
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February 2018 in “European Journal of Immunology” Regulatory T cells are essential for normal and improved wound healing in mice.