31 citations
,
December 1991 in “Annals of the New York Academy of Sciences” ORS and hair matrix cells balance growth and differentiation better than normal keratinocytes, with human dermal fibroblasts crucial for proper differentiation.
30 citations
,
October 2010 in “Biochemical and biophysical research communications” The Gsdma3 gene is essential for normal hair development in mice.
29 citations
,
April 2003 in “Experimental dermatology” Human hair follicles grown in vitro maintain normal keratin patterns and structure.
29 citations
,
August 1999 in “Journal of Investigative Dermatology” New mutations in hair keratin genes cause the rare hair disorder monilethrix.
28 citations
,
August 1992 in “Differentiation” A new pair of mouse keratins, 65 kD and 48 kD, are found in specific skin areas and are linked to a unique skin differentiation type.
27 citations
,
July 2015 in “International Journal of Dermatology” Every elderly patient had at least one skin condition, often linked to other diseases, highlighting the need for integrated skin and general healthcare in the elderly.
26 citations
,
October 1998 in “Experimental Dermatology” A keratin hHb6 mutation causes a hair disorder with varying severity, influenced by other factors.
24 citations
,
March 2001 in “PubMed” In Freixo de Espada à Cinta, common skin conditions include melanocytic nevi, hemangiomas, and acne, with variations based on age and sex.
24 citations
,
January 1998 in “Dermatology” Merkel cell increase is specific to certain skin diseases, not general skin growth.
23 citations
,
July 1982 in “International Journal of Dermatology” The review concludes that accurate diagnosis of different types of hair loss requires proper biopsy techniques and understanding the hair growth cycle and underlying causes.
21 citations
,
January 2022 in “Pharmaceutics” Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.
21 citations
,
June 2017 in “Case Reports in Dermatology” Reducing gefitinib dosage improved hair loss, but scarring remained.
21 citations
,
May 2014 in “Toxicological Sciences” Toluene diisocyanate exposure can cause immune sensitization by interacting with proteins in hair follicles and sebaceous glands.
21 citations
,
January 2010 in “International journal of trichology” Trichoscopy can diagnose monilethrix, a genetic hair defect causing hair thinning and loss.
21 citations
,
September 1997 in “British Journal of Dermatology” Monilethrix is linked to the type II keratin gene on chromosome 12q13.
20 citations
,
December 2010 in “Journal of Morphology” Lizard claws have hair-like keratins similar to those in mammals.
20 citations
,
July 2006 in “Veterinary dermatology” Melatonin helped some Pomeranian dogs regrow hair, but it wasn't linked to estrogen receptors.
19 citations
,
April 1999 in “British Journal of Dermatology” Keratin 2e shows a unique pattern in developing fetal skin, different from other keratins.
17 citations
,
July 2014 in “Our Dermatology Online” Older adults have a wide range of skin conditions, with dry skin being very common and many also experiencing skin growths, itching, and infections.
17 citations
,
April 2006 in “Dermatologic Clinics” Older women face various skin issues like dryness and thinning, and treatments are available but can have side effects; proper skin care and legal health decisions are important.
16 citations
,
August 2015 in “Journal of Experimental & Clinical Cancer Research” The photolyase-based device significantly changed the size and heat of potential skin cancer areas in patients.
15 citations
,
October 2022 in “Allergy” Dupilumab treatment reduces Th2-related markers and helps hair growth in alopecia areata, showing Th2's role in the condition.
14 citations
,
April 2019 in “PLOS ONE” Skin cancer is common in elderly nursing home residents, with risk factors including being male, having light skin, outdoor work history, and smoking. Regular skin checks are recommended.
14 citations
,
September 2016 in “Journal of Photochemistry and Photobiology B Biology” UV exposure damages hair, increasing thiols and altering protein structure.
14 citations
,
April 1995 in “Transplantation” Human hair follicle cells can be used to help heal and replace skin.
13 citations
,
January 2018 in “Skin Appendage Disorders” Dermoscopy improves diagnosis and treatment planning for trichostasis spinulosa.
13 citations
,
March 2000 in “Veterinary Dermatology” Dogs have a skin condition like human pseudopelade, causing hair loss that doesn't improve with treatment.
11 citations
,
March 2001 in “Clinics in Dermatology” Hair microscopy is useful for diagnosing hair disorders, but clear definitions are needed for accurate genetic analysis.
10 citations
,
December 2015 in “International Journal of Dermatology” CK 15, follistatin, and Bmi-1 can help differentiate basal cell carcinoma from squamous cell carcinoma.
9 citations
,
July 2017 in “Dermatologic Therapy” Two elderly men developed scalp inflammation after using a gel for skin lesions, which healed with treatment except for some permanent hair loss.