research Characters of KRT80 and its roles in neoplasms diseases
KRT80 may worsen cancer by increasing growth and spread, but its full effects on treatment and outcomes need more research.
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research In vitro assembly properties of human type I and II hair keratins
research Serial cultivation of human scalp hair follicle keratinocytes
A method was developed to grow millions of hair cells from a single hair for research and storage.
research 486 Molecular Mechanisms of Type II Spiral Ganglion Neuron Development
research May the best wound WIHN: the hallmarks of wound-induced hair neogenesis
Wounds can cause new hair growth in adult mice, influenced by Wnt signaling.
research Investigation of the Anti-Aging Effects of Composite Nanocarriers Based on Autophagy Regulation and Oxidative Stress Inhibition
RCDP NCs are promising anti-aging cosmetic ingredients that improve skin health by reducing oxidative stress and enhancing cell function.
research Ornithine Decarboxylase Expression Leads to Translocation and Activation of Protein Kinase CK2 in Vivo
High ornithine decarboxylase levels may lead to hair loss and cancer by increasing CK2 activity in the nucleus.
research The global regulatory logic of organ regeneration: circuitry lessons from skin and its appendages
Understanding molecular pathways is key to improving organ regeneration.
research An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice ( Acomys )
High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
research Treatment of a Spinal Cord Hemitransection Injury with Keratin Biomaterial Hydrogel Elicits Recovery and Tissue Repair
Keratin hydrogel from human hair helps rats recover better from spinal cord injuries.
research Pigmentation of regenerated hairs after wounding
Regenerated hairs can regain their color if the wound occurs during a certain stage of hair growth, and this process is helped by specific skin cells and proteins.
research 267 Single- and multiple-ascending dose studies of DS-2325a, a KLK5 inhibitor for the treatment of Netherton syndrome
DS-2325a is safe and well-tolerated, supporting further development for Netherton Syndrome treatment.
research Targeted expression of activated erbB-2 to the epidermis of transgenic mice elicits striking developmental abnormalities in the epidermis and hair follicles.
Activated erbB-2 in mice skin causes severe skin and hair abnormalities.
research Liposome-Based Carriers for CRISPR Genome Editing
Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.
research Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model
Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.
research Characterization of Human Keratin-Associated Protein 1 Family Members
Mutations in hKAP1 genes may cause hereditary hair disorders.
research A Missense Mutation within the Helix Initiation Motif of the Keratin K71 Gene Underlies Autosomal Dominant Woolly Hair/Hypotrichosis
A specific gene mutation causes woolly hair and hair loss.
research The ultrastructure of the interfollicular epidermis of the hairless (hr/hr) mouse
research Application of second near infrared fluorescence imaging to trace CelTrac1000-labeled hair follicle epidermal neural crest stem cells in repairing rat facial nerve defects
NIR-II imaging effectively tracked stem cells that helped repair facial nerve defects in rats.
research Data from Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy
Activating certain cells in hair follicles can prevent hair loss caused by cancer treatments.
research Human hair follicle pluripotent stem (hfPS) cells promote regeneration of peripheral‐nerve injury: An advantageous alternative to ES and iPS cells
Human hair follicle stem cells can safely and effectively help nerve regeneration.
research Nerves of Hair
Keratin-based hydrogels from human hair help nerve repair better than traditional methods.
research Monilethrix: the use of tricoscopy in clinical diagnosis
Monilethrix is a genetic disorder causing brittle hair, diagnosed using tricoscopy.
research Rational Design of Human Hair Keratin−Driven Proteins for Hair Growth Promotion
RK81 can help promote hair growth.
research Genetic disorders of keratin: are scarring alopecias a sub-set?
Keratin mutations may cause scarring alopecia by damaging hair structure.
research Bioinspired Strategies for Wound Regeneration
Combining biochemical, immune, and mechanical signals can improve skin regeneration.
research Mouse Epidermal Neural Crest Stem Cell (EPI-NCSC) Cultures
Mouse epidermal neural crest stem cells can become various cell types and are easily obtained from hair follicles.
research Effects of implanted human hair keratin on the neural function and morphologic change of injured spinal cord in adult rats
Human hair keratin may help repair injured spinal cord tissue in rats.
research Author response: Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin
ERK activation spreads between cells, influencing cell division and wound healing.
research 354 Investigating early molecular changes in a model of x-ray radiation-induced alopecia: spotlight on growth arrest and endothelial dysfunction
Radiation-induced hair loss may be caused by hair growth stopping and inflammation in blood vessels.