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research Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage

441 citations , May 1996 in “Journal of Cell Science”

Keratin 19 helps identify skin stem cells, with its presence varying by body location, age, and culture stage.

research Corrections to: "The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle"

May 2010 in “Journal of Investigative Dermatology”

research Identification of the C-terminal tail domain of AHF/trichohyalin as the critical site for modulation of the keratin filamentous meshwork in the keratinocyte

12 citations , December 2011 in “Journal of Dermatological Science”

The C-terminal tail of AHF/trichohyalin is essential for organizing keratin filaments in keratinocytes.

research Lipid signaling in keratinocytes: Lipin-1 plays a PArt

1 citations , April 2016 in “Journal of lipid research”

Lipin-1 is important for skin cell differentiation and skin barrier function.

research A curated catalog of canine and equine keratin genes

20 citations , August 2017 in “PLoS ONE”

61 functional keratin genes were identified in dogs and horses, leading to updated gene annotations.

research Trichohyalin: Purification from Porcine Tongue Epithelium and Characterization of the Native Protein

16 citations , June 1992 in “Journal of Investigative Dermatology”

research Histochemical observations of lectin-binding sites and keratin distribution in calcifying epithelioma of Malherbe.

6 citations , January 1985 in “ACTA HISTOCHEMICA ET CYTOCHEMICA”

Tumor cells in calcifying epithelioma of Malherbe resemble hair follicle cells.

research The HOXC13-controlled expression of early hair keratin genes in the human hair follicle does not involve TALE proteins MEIS and PREP as cofactors

18 citations , November 2005 in “Archives of Dermatological Research”

research 454 Modeling epidermolysis bullosa simplex with cardiomyopathy using KLHL24-mutant pluripotent stem cells.

November 2025 in “Journal of Investigative Dermatology”

KLHL24-mutant stem cells help understand skin and heart disease.

research Histogenesis of keratoacanthoma: histochemical and immunohistochemical study

16 citations , October 2014 in “Oral surgery, oral medicine, oral pathology and oral radiology”

Keratoacanthoma comes from hair follicle cells.

research Salute to Surgeon of the Month

September 2002 in “Hair transplant forum international”

The document's conclusion cannot be provided because the content is not available.

research Salute to Surgeon of the Month

January 2002 in “Hair transplant forum international”

The document's conclusion cannot be provided because the content is not available.

Efficient Genome Editing Using CRISPR/Cas9 Ribonucleoprotein Approach in iPS Cells for Recessive Dystrophic Epidermolysis Bullosa

research 924 Efficient genome editing using CRISPR/Cas9 ribonucleoprotein approach in iPS cells for recessive dystrophic epidermolysis bullosa

April 2019 in “Journal of Investigative Dermatology”

Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.

Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)

research Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)

6 citations , September 2015 in “Journal of Medicinal Chemistry”

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

research Ultrastructural localization of hair keratins, high sulfur keratin-associated proteins and sulfhydryl oxidase in the human hair

9 citations , February 2016 in “Anatomical Science International”

Hair proteins change location and structure as hair cells mature.

research Defining a Region of the Human Keratin 6a Gene That Confers Inducible Expression in Stratified Epithelia of Transgenic Mice

44 citations , May 1997 in “Journal of Biological Chemistry”

The human keratin 6a gene's specific sequences trigger expression in skin layers after injury.

research Mrp3, a Mitogen-Regulated Protein/Proliferin Gene Expressed in Wound Healing and in Hair Follicles

19 citations , May 2001 in “Endocrinology”

Mrp3 may aid in wound healing and hair growth.

research [Immunohistochemical study on the keratin expression in generating rat hair tissues using anti-hair keratin monoclonal antibodies].

July 1990 in “PubMed”

Hair germ cells differ from epidermal cells in keratin expression, and specific keratins form after hair differentiation.

research Skin Keratins

54 citations , November 2015 in “Methods in enzymology on CD-ROM/Methods in enzymology”

Keratins are important for skin cell health and their problems can cause diseases.

research Data from Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity

March 2023

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

research Development of a new therapeutic approach based on peptide nanoparticles delivering CRISPR-Cas9 for the specific targeting of KRAS mutations

September 2023 in “HAL (Le Centre pour la Communication Scientifique Directe)”

Peptide nanoparticles can effectively deliver CRISPR-Cas9 to target KRAS mutations in cancer.

research DNMT1 targets SRD5A2 to induce mitochondrial homeostasis and EMT in urothelial cells of hypospadias

April 2025 in “Molecular Biology Reports”

DNMT1 may help treat hypospadias by improving cell function and preventing unwanted cell changes.

research Cornification in reptilian epidermis occurs through the deposition of keratin‐associated beta‐proteins (beta‐keratins) onto a scaffold of intermediate filament keratins

33 citations , October 2012 in “Journal of Morphology”

Reptile skin hardens by layering beta-proteins on keratin.

research Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for β-catenin and Notch signalling

84 citations , September 2008 in “Developmental biology”

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

research Both Retinoic Acid Receptors α (RARα) and γ (RARγ) Are Able to Initiate Mouse Upper-Lip Skin Glandular Metaplasia

10 citations , August 1998 in “Journal of Investigative Dermatology”

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Research

research Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage

research Corrections to: "The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle"

research Identification of the C-terminal tail domain of AHF/trichohyalin as the critical site for modulation of the keratin filamentous meshwork in the keratinocyte

research Lipid signaling in keratinocytes: Lipin-1 plays a PArt

research A curated catalog of canine and equine keratin genes

research Trichohyalin: Purification from Porcine Tongue Epithelium and Characterization of the Native Protein

research Histochemical observations of lectin-binding sites and keratin distribution in calcifying epithelioma of Malherbe.

research The HOXC13-controlled expression of early hair keratin genes in the human hair follicle does not involve TALE proteins MEIS and PREP as cofactors

research 454 Modeling epidermolysis bullosa simplex with cardiomyopathy using KLHL24-mutant pluripotent stem cells.

research Histogenesis of keratoacanthoma: histochemical and immunohistochemical study

research Salute to Surgeon of the Month

research Salute to Surgeon of the Month

research 924 Efficient genome editing using CRISPR/Cas9 ribonucleoprotein approach in iPS cells for recessive dystrophic epidermolysis bullosa

research Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)

research Heat shock protein 25 plays multiple roles during mouse skin development

research CLED: A Calcium-Linked Protein Associated with Early Epithelial Differentiation

research 085 Post-translational regulation of hair keratins in transfected COS-1 cells

research Cloning and Expression of Cellular Retinoic Acid Binding Protein I Gene in Inner Mongolian Cashmere Goats

research Keratin expression in the normal nail unit: markers of regional differentiation

research Ultrastructural localization of hair keratins, high sulfur keratin-associated proteins and sulfhydryl oxidase in the human hair

research Defining a Region of the Human Keratin 6a Gene That Confers Inducible Expression in Stratified Epithelia of Transgenic Mice

research Mrp3, a Mitogen-Regulated Protein/Proliferin Gene Expressed in Wound Healing and in Hair Follicles

research [Immunohistochemical study on the keratin expression in generating rat hair tissues using anti-hair keratin monoclonal antibodies].

research Skin Keratins

research Data from Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity

research Development of a new therapeutic approach based on peptide nanoparticles delivering CRISPR-Cas9 for the specific targeting of KRAS mutations

research DNMT1 targets SRD5A2 to induce mitochondrial homeostasis and EMT in urothelial cells of hypospadias

research Cornification in reptilian epidermis occurs through the deposition of keratin‐associated beta‐proteins (beta‐keratins) onto a scaffold of intermediate filament keratins

research Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for β-catenin and Notch signalling

research Both Retinoic Acid Receptors α (RARα) and γ (RARγ) Are Able to Initiate Mouse Upper-Lip Skin Glandular Metaplasia