November 2023 in “Scientific Reports” A gene mutation in Lama3 is linked to a common type of hair loss.
Atopy and altered T cell functions contribute to Alopecia Areata.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The ALADIN score can predict how well patients with alopecia areata will respond to JAK inhibitor treatments.
77 citations
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June 2002 in “Journal of Investigative Dermatology” CD44 variant changes start alopecia areata, but don't maintain it.
May 2023 in “The Journal of Immunology” Alopecia areata involves unique activation of certain immune cells.
January 2025 in “Annals of Thoracic and Cardiovascular Surgery” Removing the thymoma improved the patient's alopecia areata, suggesting a possible link between the two.
12 citations
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April 2017 in “Experimental and Therapeutic Medicine” Patients with severe active alopecia areata have lower CD200 expression and an imbalance in their immune system.
Alopecia areata is an autoimmune disease affecting hair follicles and may harm heart health.
July 1975 in “Archives of Dermatology” The document suggests a possible connection between rapid weight loss and hair loss, and reports a case of skin condition improvement after stopping acne medication.
20 citations
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June 2010 in “Genes and Immunity” Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
5 citations
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January 2012 in “PubMed” Anti-MND antibodies are present in various diseases, not just PBC, and their levels don't correlate with disease activity or skin symptoms.
32 citations
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August 2016 in “Science Signaling” Alopecia areata patients show unique protein activity patterns, suggesting imbalanced signaling pathways.
3 citations
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October 2024 in “Archives of Dermatological Research” Alopecia areata is linked to blood cancers, especially in older patients, but not to most solid cancers.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” ILC1-like cells can cause alopecia areata by attacking hair follicles.
ILC1-like cells can independently cause alopecia areata by affecting hair follicles.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Linoleic acid and magnesium are key in alopecia areata progression, and tofacitinib can help by affecting their pathway.
23 citations
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September 2019 in “Dermatology practical & conceptual” The study concluded that AAI and DAA are forms of the same disease, with different symptoms in men and women, and that corticosteroid treatment is effective.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” People with alopecia areata have fewer IL-10 producing immune cells, which might contribute to the condition.
June 2023 in “British journal of dermatology/British journal of dermatology, Supplement” A woman's rare hair loss condition improved on its own, suggesting this type might recover like common cases.
5 citations
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September 2021 in “Journal of cosmetic dermatology” People with alopecia areata often have abnormal thyroid hormones, thyroid antibodies, antinuclear antibodies, low vitamin D, and high C-reactive protein levels.
2 citations
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March 2025 in “Journal of Translational Autoimmunity” Targeting the AhR pathway may help treat alopecia areata.
April 2023 in “Journal of Investigative Dermatology” CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Targeting specific metabolic and ionic pathways may improve alopecia areata treatment.
November 2025 in “Journal of Investigative Dermatology” Certain CD8+ T cells attack hair follicles in alopecia areata, suggesting they could be targeted for treatment.
30 citations
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October 2013 in “Lupus” Hair loss in lupus is different from hair loss in alopecia areata and may indicate lupus activity.
31 citations
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June 2011 in “Movement Disorders” The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.
April 2025 in “Dermatology Practical & Conceptual” Alopecia areata patients have higher systemic inflammation, even in mild cases.
1 citations
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July 2019 in “Clinical Rheumatology” Leflunomide is more likely to help treat alopecia areata than cause it.
4 citations
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January 2023 in “Skin Appendage Disorders” Changes in certain RNA and protein levels may contribute to alopecia areata and could be treatment targets.
October 2024 in “Benha Medical Journal” Patients with Alopecia Areata have higher levels of certain inflammatory markers.