research The role of tight junctions in skin barrier function and dermal absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
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research Hormones and the pilosebaceous unit
Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
research Ultraviolet B irradiation increases the expression of inflammatory cytokines in cultured sebocytes
UV-B light increases inflammation-related substances in acne-related skin cells.
research Expression Pattern of Cyclooxygenase-2 in Normal Rat Epidermis and Pilosebaceous Unit during Hair Cycle
COX-2 levels change during the hair cycle and affect skin and hair growth.
research Tracing selection signatures in the pig genome gives evidence for selective pressures on a unique curly hair phenotype in Mangalitza
Selective breeding caused the unique curly hair in Mangalitza pigs.
research What’s Diet Got to Do With It? Basic and Clinical Science Behind Diet and Acne
Diet may influence acne development.
research Alpha linolenic acid and linoleic acid and their effects on therapeutic regimen of canine dermatoses
Alpha linolenic acid and linoleic acid help treat inflammatory skin conditions in dogs.
research Polymorphisms in Genes Involved in Steroidogenesis in the Development of Severe Acne
Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.
research Comparison of Complications that Arise after DT and FCLT in the Treatment of Post-Acne Scars
The dermaroller caused less hyperpigmentation and no itching compared to the fractional CO2 laser.
research Scalp Sebaceous Physiology
The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.
research Proposed mechanisms of low-level light therapy in the treatment of androgenetic alopecia
LLLT helps treat hair loss by increasing blood flow, reducing inflammation, and stimulating growth factors.
research What should be kept in mind when treating acne with oral contraceptives? Narrative review
Oral contraceptives can effectively treat acne by reducing oil production.
research Hair dermal papilla cell metabolism is influenced by minoxidil
research A subpopulation of itch‐sensing neurons marked by Ret and somatostatin expression
Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
research Sebaceous Gland, Hair Shaft, and Epidermal Barrier Abnormalities in Keratosis Pilaris with and without Filaggrin Deficiency
Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.
research Mandibulofacial dysostosis with alopecia results from ETAR gain-of-function mutations via allosteric effects on ligand binding
Specific mutations in a receptor cause facial abnormalities and hair loss.
research Measurement of Acne Severity, Dietary Habits, and Blood Zonulin Levels in Acne Patients
Diet and gut health may influence acne development.
research Potential Causal Relationship Between Extensive Lipid Profiles and Various Hair Loss Diseases: Evidence From Univariable and Multivariable Mendelian Randomization Analyses
Managing lipids may help treat hair loss.
research Altered Hormone and Bioactive Lipid Plasma Profile in Rodent Models of Polycystic Ovarian Syndrome Revealed by Targeted Mass Spectrometry
Rodent models of PCOS show some similar and some different lipid changes compared to humans.
research Recurrent pruritic polymorphic lesions associated with weight loss
A man with itchy skin lesions and weight loss was diagnosed with a rare skin condition linked to a pancreatic tumor.
research Advances in histamine-mediated allergy management: Expanding perspectives on cetirizine’s therapeutic, safety, and toxicological implications
Cetirizine is effective and safe for treating various allergies, with personalized dosing improving its use.
research Biologics in the management of childhood atopic dermatitis
Biologics, especially Dupilumab, are effective and safe for treating severe childhood eczema.
research Prescribers alerted to potential adverse effects of finasteride and montelukast
research Drug Information Analysis Service
Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.
research The effect of 5-α reductase inhibitor on Th1, Th2, and Th17 cell-related inflammatory response in BPH
Finasteride reduces some inflammation in BPH but not all.
research Image3_Neuropsychiatric Adverse Events of Montelukast: An Analysis of Real-World Datasets and drug−gene Interaction Network.TIFF
Montelukast is linked to increased risks of suicidal thoughts and depression.
research ZAOSTRZENIA NIEWYDOLNOŚCI ODDECHOWEJ- PRZYCZYNY I POSTĘPOWANIE
COPD flare-ups worsen life quality and increase hospital visits and costs.
research Safety of Biological Therapies for Severe Asthma: An Analysis of Suspected Adverse Reactions Reported in the WHO Pharmacovigilance Database
Biologics for severe asthma have known side effects, but some new risks need more study.
research 1113 Targeting anti-inflammatory immunonanocarriers to human and murine neutrophils via Ly6 antigen for psoriasiform dermatitis alleviation
The study created special nanoparticles that effectively deliver an anti-inflammatory drug to treat skin inflammation in psoriasis.
research Phosphodiesterase (PDE) Inhibitors for the Treatment of Inflammatory Skin Conditions
PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.