31 citations
,
September 2006 in “The Journal of Clinical Endocrinology & Metabolism” Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.
29 citations
,
January 2011 in “Journal of Obstetrics and Gynaecology” Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.
23 citations
,
July 1989 in “Postgraduate medical journal” Spironolactone did not make hair thinner in women with excess hair growth.
21 citations
,
June 2016 in “Reproductive Sciences” Women with PCOS, especially those overweight, have higher levels of IL-18 in their endometrium, which may affect fertility.
20 citations
,
July 2009 in “Journal of Pediatric and Adolescent Gynecology” Quick treatment of hair disorders in teenage girls is important because of the emotional effects.
16 citations
,
November 2018 in “Singapore Medical Journal” Primary care for PCOS focuses on lifestyle changes, medication based on symptoms, and mental health, with diabetes screening and specialist referral for severe cases.
11 citations
,
April 2017 in “The European Journal of Contraception & Reproductive Health Care” Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.
9 citations
,
January 1997 in “Gynecological Endocrinology” The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
2 citations
,
February 2021 in “Endocrinology, diabetes & metabolism case reports” A teenage girl had both a rare ovarian tumor and a severe form of polycystic ovarian syndrome.
1 citations
,
March 2024 in “Türk Kadın Sağlığı ve Neonatoloji Dergisi” PCOS is common in women, often treated with lifestyle changes and oral contraceptives.
1 citations
,
January 2017 in “Spectrum Research Repository (Concordia University)” Women with PCOS have altered brain structure and reduced cognitive performance.
PCOS has a strong genetic basis, but more research is needed to fully understand it.
January 2025 in “Current Trends in Pharmacy and Pharmaceutical Chemistry” New methods for measuring dutasteride are effective and reliable.
February 2024 in “Journal of Health Science and Medical Therapy” ADAM17 could be a potential target for treating PCOS.
January 2023 in “Archives of Disease in Childhood Education & Practice” Hirsutism in teens is often due to polycystic ovarian syndrome and needs careful assessment and support.
July 2020 in “International Journal of Research” High testosterone increases heart disease risk in women with PCOS.
December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” Steroid-producing capabilities in certain cancers may contribute to treatment resistance.
December 2015 in “University of Birmingham Institutional Research Archive (University of Birmingham)” AKR1C3 could be a treatment target for metabolic issues in PCOS.
August 2014 in “Warwick Research Archive Portal (University of Warwick)” Obesity negatively affects the endometrium, leading to higher miscarriage risk and impaired cell function.
April 2011 in “Global journal of health science” Aldactone effectively reduces hair thickness in women with excessive hair growth, both alone and with other treatments.
April 2011 in “Global journal of health science” Spironolactone effectively makes hair shafts thinner in women with excessive hair growth.
January 2019 in “Indian Dermatology Online Journal” Stress, hypothyroidism, drug intake, and anemia are important factors in women's diffuse hair loss.
2 citations
,
November 2015 in “Endocrinology, Diabetes & Metabolism Case Reports” A man with X-ALD improved after treatment, highlighting the need to consider X-ALD in similar patients and test their relatives.
4 citations
,
September 2006 in “European Urology Supplements” Dutasteride reduces DHT and improves BPH symptoms more effectively than finasteride.
2 citations
,
October 2024 in “Endocrine Connections” Lower adiponectin levels are linked to higher insulin resistance in women with PCOS.
May 2018 in “Journal of Saidu Medical College Swat” Hirsutism in Afghan women varies by community, influenced by awareness, education, and socio-economic status.
January 2018 in “Biomedical Research (Aligarh)” Women with early-onset baldness should be checked for early bone loss, but bone density doesn't change with baldness severity.
11 citations
,
January 2024 in “Gynecological Endocrinology” Myo-inositol and D-chiro-inositol, especially in a 40:1 ratio, effectively treat PCOS by improving insulin sensitivity and ovulation.
8 citations
,
December 2022 in “International journal of molecular sciences” Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
7 citations
,
August 2023 in “EClinicalMedicine” Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.