72 citations
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January 2023 in “International Journal of Biological Sciences” Engineered exosomes show promise for improving wound healing but face challenges in clinical use.
94 citations
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June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
54 citations
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April 2020 in “Experimental & Molecular Medicine” Cox-2 significantly contributes to the development and progression of skin and esophageal cancers.
10 citations
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May 2019 in “Seminars in Cell & Developmental Biology” Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
18 citations
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July 2021 in “Molecular Medicine Reports” The WNT signaling pathway is crucial for mesenchymal stem cells' function and therapy success.
10 citations
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October 2016 in “Experimental Dermatology” Nail stem cells and Wnt signaling are important for fingertip regeneration but not sufficient for regenerating more complex limb structures.
April 2024 in “Pigment cell & melanoma research” Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.
58 citations
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August 2015 in “The Indonesian Biomedical Journal” Different types of stem cells help maintain and heal skin.
33 citations
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May 2018 in “Stem Cell Reports” Krt15+ cells in the mouse intestine resist radiation and can start tumors.
3 citations
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December 2024 in “Stem Cell Reports” Low fucosylation boosts stem cell growth in the eye.
April 2026 in “International Journal of Molecular Sciences” Wnt signaling is crucial for skin, hair, and nail health and regeneration.
April 2017 in “Journal of Dermatological Science” Asymmetric hair follicle differentiation causes the unique shape of kinky hair.
14 citations
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May 2017 in “Cell metabolism” Paneth cells and intestinal stem cells work together metabolically for stem cell function and regeneration.
7 citations
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July 2024 in “Current Issues in Molecular Biology” Understanding skin stem cells and their regulation is key to improving skin healing and treating disorders.
January 2024 in “Updates in clinical dermatology” 105 citations
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October 2018 in “Nature” A small group of slow-growing cells causes basal cell carcinoma to return after treatment.
79 citations
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November 2016 in “EMBO Reports” Disruptions in mammary stem cell division can lead to cancer, but targeting these processes might help treat breast cancer.
7 citations
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August 2020 in “Genes” Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.
January 2024 in “Journal of developmental biology” Abdominal skin heals faster than dorsal skin because it has more stem cells.
2 citations
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August 2006 in “Journal of Dermatological Science” Automated image analysis helps diagnose and monitor alopecia areata by efficiently measuring hair follicles.
1 citations
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January 2012 in “Pigment Cell & Melanoma Research” Stem cell niches are crucial for maintaining stem cells, with Paneth cells and TGF-beta playing key roles.
4 citations
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November 2017 in “PubMed” Your genes, especially IL-1a, can predict how well a hair growth treatment with platelet rich plasma will work for you.
2 citations
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February 2025 in “PLoS ONE” Key proteins influence wool quality by affecting hair follicle development in sheep.
129 citations
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July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
180 citations
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January 2011 in “EMBO Reports” A combined approach is needed to fully understand adult stem cells, with genetic lineage-tracing being crucial.
55 citations
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March 2014 in “EMBO Reports” Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.
19 citations
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December 2023 in “Journal of Investigative Dermatology” Scalp hair follicle microbes affect hair health and could be used for treatments.
2 citations
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December 2024 in “BMC Genomics” Key genes and pathways control sheep hair growth phases.
6 citations
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November 2023 in “Stem Cell Reports” Stem cells in the cornea show unexpected flexibility and have important implications for medicine.
The research identified key molecules that help hair matrix and dermal papilla cells communicate and influence hair growth in cashmere goats.