56 citations
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July 2014 in “PLoS ONE” Midazolam reduces PTSD-like behavior in rats by acting on specific brain receptors.
55 citations
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April 2010 in “Cancer and Metastasis Reviews” TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
51 citations
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June 2021 in “Signal Transduction and Targeted Therapy” The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
46 citations
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August 2019 in “Journal of Ethnopharmacology” Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.
33 citations
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August 2024 in “Frontiers in Drug Discovery” Drug repurposing is a faster, cheaper way to develop new treatments using existing drugs.
30 citations
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October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
24 citations
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July 2017 in “Structure” FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.
20 citations
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March 2013 in “Journal of Lipid Research” The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.
18 citations
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January 2019 in “Experimental Dermatology” Certain cells outside the hair follicle's bulge area can quickly regenerate damaged hair follicles, potentially helping to reduce hair loss from cancer treatments.
17 citations
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January 2015 in “MedChemComm” New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
16 citations
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March 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
16 citations
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December 2012 in “Bioinformation” Curcumin, EGCG, barringtozenol, and finasteride are effective VEGFR inhibitors.
11 citations
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July 2014 in “Gene” The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.
6 citations
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April 2025 in “Plastic and Aesthetic Research” Biomaterial characteristics can influence macrophages to promote healing and improve tissue regeneration.
6 citations
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October 2016 Understanding how keratin structures in hair are arranged and interact is key for creating methods to extract and purify them.
4 citations
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January 2018 in “Cancer treatment and research” The document concludes that systemic therapy is becoming more important in treating head and neck cancer, with new treatments showing promise.
2 citations
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November 2022 in “Acta crystallographica. Section B, Structural science, crystal engineering and materials./Acta crystallographica. Section B, Structural science, crystal engineering and materials” A new platinum complex was made and studied, which might help fight cancer better.
2 citations
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June 2023 in “Food science & nutrition” Eating apples can help prevent heart disease, cancer, and other conditions because they have healthy plant chemicals.
1 citations
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January 2026 in “Frontiers in Bioengineering and Biotechnology” Ionizable lipid nanoparticles are the best for delivering gene-editing therapies.
1 citations
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August 2025 Drug repurposing can speed up and reduce costs in drug discovery, especially for cancer treatment.
1 citations
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March 2019 in “Actas Dermo-Sifiliográficas” New cancer treatments are less harmful to hair but can still cause hair loss, color, shape, and growth changes.
1 citations
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February 2025 in “South Asian Research Journal of Pharmaceutical Sciences” Eclipta alba flavonoids may help treat diabetes by effectively inhibiting Aldose reductase.
Vitamin D is crucial for skin health and managing skin diseases.
January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Semecarpus anacardium leaf extracts may offer safe, effective cancer treatment alternatives.
January 2019 in “Springer Reference Medizin” Follicle Stimulating Hormone is important for fertility.
May 2015 in “Journal of Investigative Dermatology” Wnt-3a helps grow more skin stem cells, which could lead to new hair loss treatments.
The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.
April 2016 in “Journal of Investigative Dermatology” A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.
January 2016 in “Human & Experimental Toxicology” A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.
June 2013 in “Revista cubana de plantas medicinales” Sida cordifolia is rich in saponins with antioxidant and antifungal properties.