research Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation
mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.
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research Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream
The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.
research Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice
15-lipoxygenase helps keep skin healthy by reducing inflammation.
research Inactivation of autophagy leads to changes in sebaceous gland morphology and function
Autophagy is crucial for normal sebaceous gland function and sebum composition.
research Association of Insulin Resistance with Hyperandrogenia in Women
Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.
research Optimization of menthol-loaded nanocapsules for skin application using the response surface methodology
Researchers created better skin-application menthol capsules that are stable, safe, and penetrate the skin quickly.
research The effects of particle properties on nanoparticle drug retention and release in dynamic minoxidil foams
Particle properties affect drug retention and release in minoxidil foams, with lipid nanoparticles having higher loading capacity.
research The role of lysophosphatidic acid in the physiology and pathology of the skin
Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
research Hair Growth Cycle Is Arrested in SCD1 Deficiency by Impaired Wnt3a-Palmitoleoylation and Retrieved by the Artificial Lipid Barrier
An artificial lipid barrier can restore hair growth in cases of SCD1 deficiency.
research What is the Rationale for Androgen Therapy for Women?
Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.
research Anti-PDGF receptor β antibody-conjugated squarticles loaded with minoxidil for alopecia treatment by targeting hair follicles and dermal papilla cells
Scientists created tiny particles loaded with a hair growth drug, minoxidil, that specifically target hair follicles and skin cells to potentially improve hair growth.
research Final Report on the Safety Assessment of Human Placental Protein, Hydrolyzed Human Placental Protein, Human Placental Enzymes, Human Placental Lipids, Human Umbilical Extract, Placental Protein, Hydrolyzed Placental Protein, Placental Enzymes, Placental Lipids, and Umbilical Extract
The safety of placental and umbilical extracts in cosmetics is uncertain, requiring more research.
research Metabolic dysfunction in female mice with disruption of 5α-reductase 1
Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
research From stem cells protection to skin microbiota balance: Orobanche rapum extract, a new natural strategy
Orobanche rapum extract rejuvenates skin and protects skin bacteria, leading to healthier skin.
research Matriptase Expression and Zymogen Activation in Human Pilosebaceous Unit
Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.
research 6‐O glucose linoleate supports in vitro human hair growth and lipid synthesis
6-O glucose linoleate helps human hair grow and produce lipids.
research Forsythiaside A Activates AMP-Activated Protein Kinase and Regulates Oxidative Stress via Nrf2 Signaling
Forsythiaside A helps protect cells and liver from damage by reducing oxidative stress and boosting antioxidants.
research Engineered Dutasteride-Lipid Based Nanoparticle (DST-LNP) System Using Oleic and Stearic Acid for Topical Delivery
The formulation with oleic acid may be better for treating male pattern baldness.
research Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis
Skin acetyl-CoA synthesis is crucial for overall lipid balance.
research Hair in health and disease: an introduction
Hair health depends on various factors and hair loss can significantly affect a person's well-being; understanding hair biology is key for creating effective hair care treatments.
research Studies on the efficacy of methyl esters of n-alkyl fatty acids as penetration enhancers
Methyl caprate greatly increases drug absorption through the skin and is better than other enhancers.
research 4-O-Methylhonokiol: A lesser-known neolignan from Magnolia species with diverse and promising pharmacological properties
4-O-Methylhonokiol from Magnolia shows promise for hair growth, cancer, diabetes, and more, but needs better absorption.
research ANDROGRAPHOLIDE LOADED TOPICAL NANOCARRIERS FOR MANAGEMENT OF PSORIASIS: A SAFE AND EFFECTIVE APPROACH
Andrographolide-loaded topical nanocarriers are a safe and effective treatment for psoriasis.
research Cicatricial Alopecia
Early diagnosis and aggressive treatment are crucial for Cicatricial Alopecia, and treatment effectiveness varies among patients.
research Sebum Production
Sebum production varies by individual and is influenced by age, gender, and hormones, affecting skin and hair health.
research Current Genetics in Hair Diseases
Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.
research Assessment of adipokines, hormonal profile, lipid profile, and insulin resistance in patients with androgenetic alopecia
Androgenetic alopecia is linked to insulin resistance and hormonal imbalances.
research Topical Metformin In Dermatology: A Narrative Review Of Efficacy And Formulation Approaches
Topical metformin shows promise for treating skin conditions like acne and psoriasis.
research 0870 Improving the stability of retinol: Overcoming obstacles through solid lipid particle technology
Solid Lipid Particle technology makes retinol more stable, effective, and gentle on the skin.
research Novel delivery strategy: finasteride-loaded solid lipid nanoparticles for improved androgenetic alopecia therapy
The new delivery method for finasteride using nanoparticles may improve hair growth without skin issues.