23 citations
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May 2010 in “Surface and interface analysis” Chemical treatments and UV radiation severely damage the lipid layer on hair.
128 citations
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March 2016 in “Advanced Pharmaceutical Bulletin” Smaller nanoparticles penetrate skin better, especially through hair follicles.
71 citations
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March 2016 in “PubMed” Smaller particles improve drug delivery through the skin.
21 citations
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December 2016 in “European journal of pharmaceutics and biopharmaceutics” Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.
19 citations
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May 2010 in “Surface and interface analysis” 18-MEA is essential for hair's water resistance, and a conditioner with 18-MEA and SPDA can restore it.
36 citations
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August 2011 in “Journal of dermatological science” Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.
30 citations
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November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” The lipid in human hair follicles acts as a barrier, similar to the skin's lipid layer.
52 citations
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January 2020 in “Scientific Reports” NLCs with manual massage greatly improve clobetasol delivery to hair follicles.
32 citations
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January 2017 in “PLoS ONE” Adiponectin boosts lipid production in skin cells, potentially helping treat skin conditions with low sebum.
8 citations
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February 2022 in “International Journal of Dermatology” Lipids are crucial for healthy hair, protecting it from damage and breakage.
7 citations
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April 2018 in “Cosmetics” Lipids in Japanese hair help maintain glossiness and structure.
6 citations
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November 1960 in “Experimental Biology and Medicine” Hair growth stages don't significantly change lipid content in mouse skin.
September 2024 in “Medical Sains Jurnal Ilmiah Kefarmasian” Nanostructured lipid carriers improve anti-aging drug delivery and effectiveness in cosmetics.
March 2024 in “Bioimpacts” 400 nm particles penetrate hair follicles best, but mouse models aren't fully reliable for human studies.
July 2022 in “International Journal of Applied Pharmaceutics” The optimized caffeine formula improved hair growth and penetrated all skin layers.
November 2021 in “Research Square (Research Square)” The new caffeine cream works better for hair growth than existing products.
November 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” Nanostructured lipid carriers can effectively deliver spironolactone to hair follicles for treating hair loss.
1 citations
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October 2017 in “ecancermedicalscience” Breast cancer alters specific molecular structures in hair, which revert after cancer removal.
425 citations
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August 2002 in “BioEssays” The cornified cell envelope forms a protective barrier in skin and hair, using specific proteins and lipids to maintain effectiveness.
107 citations
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October 2014 in “PeerJ” Hair's molecular structure is mostly consistent, but genetic differences affect lipid types, which could help diagnose diseases.
11 citations
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January 2016 in “Biointerphases” The hair's outermost surface has multiple layers of lipids and proteins.
5 citations
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August 2024 in “International Journal of Cosmetic Science” Particles stick better to healthy hair than damaged hair.
3 citations
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September 1989 in “Journal of Investigative Dermatology” Methyl caprate greatly increases drug absorption through the skin and is better than other enhancers.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Ethosomal gels improve drug delivery through the skin, enhancing treatment effectiveness.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Ethosomal gels improve drug delivery through the skin, enhancing treatment effectiveness.
The document concludes that understanding hair's composition and the effects of treatments can lead to better hair care products.
32 citations
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September 2018 in “Journal of pharmaceutical sciences” The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.
6 citations
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January 2009 in “Elsevier eBooks” The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.
1 citations
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November 2004 in “International Journal of Cosmetic Science” External agents penetrate skin more easily in areas with fewer lipids, especially through hair follicles.
April 2021 in “Journal of Investigative Dermatology” Bacteria can help skin regenerate through a process called IL-1β signaling.