research Transdermal delivery of mixnoxidil with block copolymer nanoparticles
Smaller nanoparticles improve minoxidil absorption through hair follicles.
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330-360 / 1000+ resultsresearch Novel 5α-Reductase Inhibitors: Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids
A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.
research Development of finasteride/PHBV@polyvinyl alcohol/chitosan reservoir-type microspheres as a potential embolic agent: from in vitro evaluation to animal study
Created microspheres show potential for safe and effective use in prostate artery embolization.
research In Vitro Skin Penetration of 5α-Reductase Inhibitors from Tectona grandis L.f. Leaf Extracts
Tectona grandis leaf extracts, especially with propylene glycol, may be promising for topical hair loss treatments.
research Polystyrene-b-poly (acrylic acid) nanovesicles coated by modified chitosans for encapsulation of minoxidil
Minoxidil can be effectively encapsulated in coated nanovesicles for potential drug delivery.
research Microemulsions as Carriers for Therapeutic Molecules
Microemulsions could improve how drugs are delivered and absorbed in the body.
research Drug related lipid metabolism abnormalities: a real-world pharmacovigilance exploratory analysis based on U.S. FDA adverse event reporting system (FAERS)
Many drugs can cause lipid metabolism issues, and labels need better warnings.
research Importance of Sebaceous Glands in Cutaneous Penetration of an Antiandrogen: Target Effect of Liposomes
Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.
research NANOSTRUCTURE LIPID CARRIER TECHNOLOGY IN DRUG DELIVERY: ROUTE OF ADMINISTRATION, PREPARATION METHOD, CHARACTERIZATION, AND APPLICATION FOR ANTI-AGING
Nanostructured lipid carriers improve anti-aging drug delivery and effectiveness in cosmetics.
![The Synthesis of (−)-4-Methyl-8-Chloro-Trans-1,2,3,4,4a,5,6,10b-Octahydrobenzo-[f]-Quinolin-3-One-[3-14C] (LY300502-14C) via a Circuitous Route](/images/research/73bab8dc-bdf0-45e3-8ef7-73d0d4b93cb1/small/21074.jpg)
research The synthesis of (−)-4-methyl-8-chloro-trans-1,2,3,4,4a,5,6,10b-octahydrobenzo-[f]-quinolin-3-one-[3-14C] (LY300502-14C]) via a circuitous route
Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.
research Enhanced skin penetration of lidocaine through encapsulation into nanoethosomes and nanostructured lipid carriers: a comparative study
Nanostructured lipid carriers deliver lidocaine to the skin better than nanoethosomes.
research Preparation and in vivo evaluation of lecithin-based microparticles for topical delivery of minoxidil
Lecithin-based microparticles can deliver minoxidil for hair growth effectively with less skin irritation.
research Lipid nanocosmeceuticals: a novel approach to skin therapy for anti-aging and skin disorders
Lipid-based nanocosmeceuticals improve skin therapy by enhancing ingredient delivery and effectiveness for anti-aging and skin disorders.
research Optimization and Transfollicular Delivery of Finasteride Loaded PLGA Nanoparticles Laden Carbopol Gel for Treatment of Hair Growth Stimulation
The new gel formulation effectively delivers Finasteride for hair growth treatment without skin irritation.
research Drug repositioning using in silico compound profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Development and optimization of finasteride-loaded microemulsions for transdermal delivery
Finasteride-loaded microemulsions, made with cinnamon oil, Tween20, propylene glycol, and water, can help maintain stemness of dermal cells, potentially aiding in hair regeneration.
research Analysis of metabolic characteristics of epristeride in zebrafish based on LC-Q-TOF MS and its potential applications in doping control
Epristeride's metabolism in zebrafish helps improve doping detection methods.
research Design and evaluation of adapalene microemulsion for transfollicular drug delivery through guinea pig skin
Adapalene microemulsions improve drug delivery through hair follicles, enhancing acne treatment.
research Lipid-based nanoparticles for topical delivery of hair growth therapeutic molecules
Lipid-based nanoparticles are effective for applying hair growth treatments to the skin.
research Monovalent antibody-conjugated lipid-polymer nanohybrids for active targeting to desmoglein 3 of keratinocytes to attenuate psoriasiform inflammation
The targeted nanohybrids effectively reduced psoriasis symptoms and improved skin health.
research Flutamide-Loaded Zein Nanocapsule Hydrogel, a Promising Dermal Delivery System for Pilosebaceous Unit Disorders
The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.
research Characterization of the in vitro, ex vivo, and in vivo Efficacy of the Antimicrobial Peptide DPK-060 Used for Topical Treatment
DPK-060 in poloxamer gel effectively treats skin infections, but nanocarriers don't enhance its efficacy.
research Polymeric Micelle Nanocarriers for the Cutaneous Delivery of Tacrolimus: A Targeted Approach for the Treatment of Psoriasis
New micelle nanocarriers deliver Tacrolimus more effectively to skin layers for psoriasis treatment than the current Protopic ointment.
research Minoxidil-encapsulated poly(L-lactide-co-glycolide) nanoparticles with hair follicle delivery properties prepared using W/O/W solvent evaporation and sonication
Minoxidil inside tiny particles can deliver more drug to hair follicles, potentially improving treatment for hair loss.
research An epidermis‐permeable dipeptide is a potential cosmetic ingredient with partial agonist/antagonist activity toward fibroblast growth factor receptors
Pro-Ile could be used in cosmetics to improve skin, hair growth, and healing.
research Etude de films minces et de nanoparticules obtenus par auto-assemblage de copolymères à blocs et leurs interactions avec un oligo/polysaccharide
Chitosan-decorated nanoparticles improve skin delivery of finasteride, with PS404-b-PAA63 being most effective.
research Optimizing Efficacy: Hyaluronic Acid Liposomes Encapsulating Minoxidil for Enhanced Transdermal Delivery and Treatment of Androgenetic Alopecia
A new method using hyaluronic acid liposomes improves Minoxidil's effectiveness and safety for hair growth treatment.
research Exploring the Versatility of Microemulsions in Cutaneous Drug Delivery: Opportunities and Challenges
Microemulsions could improve skin drug delivery but face challenges like complex creation and potential toxicity.
research Novel natural lipids based NLC containing finasteride improved androgenetic alopecia treatment in rats
Finasteride in lipid carriers improved hair growth in rats.
