176 citations
,
August 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
82 citations
,
March 2016 in “Autoimmunity reviews” Animal models have helped understand hair loss from alopecia areata and find new treatments.
29 citations
,
September 2012 in “Dermatologic Clinics” Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
24 citations
,
January 2008 in “KARGER eBooks” The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
21 citations
,
February 2012 in “Journal of the European Academy of Dermatology and Venereology” Late-onset alopecia areata in Taiwanese patients is more common in women, usually starts at age 57, often involves less than 10% hair loss, and may have a minimal link to thyroid issues.
18 citations
,
August 2012 in “Cutaneous and Ocular Toxicology” People with alopecia areata have higher insulin resistance.
16 citations
,
February 2018 in “Journal of Cosmetic Dermatology” Carboxytherapy may help increase hair growth in alopecia patients but requires ongoing treatment.
3 citations
,
September 2022 in “Archives of dermatological research” The fractional carbon dioxide laser is a safe and effective treatment for alopecia areata and works better than betamethasone valerate cream alone.
2 citations
,
January 2022 in “Skin appendage disorders” A combination of methotrexate injections and CO2 laser treatment led to complete hair regrowth in two patients with hard-to-treat alopecia.
2 citations
,
December 2018 in “Journal of cosmetic dermatology” Higher CRBP1 levels are linked to more severe alopecia areata.
1 citations
,
July 2023 in “Al-Azhar Medical Journal” Higher antigliadin antibodies are linked to more severe alopecia areata, suggesting screening for celiac disease in these patients.
1 citations
,
June 2023 in “Genes” Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.
July 2026 in “Quality in Sport” New treatments for alopecia areata focus on targeted drugs and regenerative therapies, but challenges remain.
June 2026 in “Research Square” Vitamin D may help with certain types of hair loss in women.
January 2024 in “Archives of dermatological research” Both treatments for alopecia areata showed similar modest effectiveness.
Combining epinephrine with a steroid may help regrow hair in severe alopecia areata cases.
January 2022 in “Al-Azhar Medical Journal” Higher antigliadin antibody levels are linked to alopecia areata severity.
16 citations
,
October 2016 in “The Journal of Dermatology” Superficial cryotherapy is effective and safe for treating alopecia areata, with better results when used early and frequently.
May 2026 in “Research Square” Children with alopecia areata often face more stress and depression, especially related to separation, which can affect their condition.
February 2026 in “Cureus” Trichoscopy helps correctly diagnose alopecia areata, not syphilitic alopecia, in patients with recent syphilis.
June 2023 in “Dermatology and therapy” The Middle East and Africa need better data, treatment consensus, and support for Alopecia Areata.
26 citations
,
September 2012 in “Journal of The American Academy of Dermatology” Patients with rapidly progressive alopecia areata often have a better outlook and shorter disease duration, with regrown fine hairs and no past alopecia being positive signs.
6 citations
,
October 2021 in “Biomedical Research and Therapy” Alopecia areata patients have higher levels of IL-6 and TNF-α.
4 citations
,
July 2025 in “Frontiers in Immunology” Early intervention with JAK inhibitors may prevent alopecia areata progression.
January 2025 in “International Journal of Dermatology Sciences” Nail changes in alopecia areata are common and may indicate severity and genetic risk.
520 citations
,
January 2017 in “AIMS biophysics” Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.
391 citations
,
January 2010 in “Journal of The American Academy of Dermatology” Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
290 citations
,
December 2017 in “Journal of The American Academy of Dermatology” Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.
226 citations
,
May 2004 in “Journal of Biological Chemistry” Collagen XXII is a marker for tissue junctions, aiding in structural integrity and found in muscles, heart, skin, and arthritic joints.
222 citations
,
September 2016 in “JCI insight” Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.