48 citations
,
February 2025 in “Nano-Micro Letters” Microneedles offer a promising, painless way to treat skin diseases but need improvements for better use.
July 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” Trichoscopy is a useful, painless tool for diagnosing and monitoring children's hair and scalp issues.
1057 citations
,
November 2011 in “Annals of Biomedical Engineering” Low-level Laser Therapy may help reduce inflammation, pain, and aid healing, but more research is needed to confirm its effectiveness and establish standard treatment guidelines.
144 citations
,
September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
88 citations
,
January 2004 in “Journal of Neuroscience” Neurosteroids regulate synaptic inhibition in the spinal cord and may help manage spinal pain.
8 citations
,
May 2018 in “Primary Care: Clinics in Office Practice” Doctors should use a detailed patient history and physical exam to diagnose joint pain, and consult a rheumatologist early for suspected autoimmune diseases.
September 2025 in “Tạp chí Da liễu học Việt Nam” Combining oral methylprednisolone with microneedle radiofrequency improves hair growth in alopecia areata but may cause pain and side effects.
15 citations
,
January 2016 in “Journal of cell science & therapy” Using a patient's own tissue for micro-grafts may effectively treat non-healing leg ulcers and relieve pain.
9 citations
,
January 2013 in “Acta dermato-venereologica” The conclusion is that "trichoknesis" should be recognized as a separate condition from trichodynia, characterized by itching instead of pain.
140 citations
,
December 2017 in “Journal of Controlled Release” Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
July 2024 in “Open Repository of the University of Porto (University of Porto)” Dutasteride is more effective than finasteride for hair growth, and pregabalin effectively treats neuropathic pain.
27 citations
,
January 2018 in “Curēus” Subcutaneous contraceptives can cause side effects like menstrual changes, headaches, weight gain, and pain at the implant site.
114 citations
,
March 2002 in “Current opinion in oncology/Current opinion in oncology, with cancerlit” Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.
165 citations
,
September 2003 in “Toxicology and applied pharmacology” Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
26 citations
,
April 2006 in “Cephalalgia” Botulinum A toxin injections reduced pain and promoted hair regrowth in a woman with a rare form of alopecia areata.
99 citations
,
August 1998 in “Pain” Blocking GABA(A) receptors increases neuron sensitivity, showing GABA and glycine have different roles in pain.
6 citations
,
March 2024 in “Saudi Pharmaceutical Journal” The new delivery system could improve pain and inflammation relief in gout.
March 2005 in “Journal of The American Academy of Dermatology” Mycophenolate mofetil improved skin condition in a man with nephrogenic fibrosing dermopathy.
1 citations
,
July 2018 in “Journal of dermatology & cosmetology” Hyaluronic acid successfully treated skin atrophy caused by corticosteroid injections.
September 2025 in “Clinical Cosmetic and Investigational Dermatology” Moderate exercise improves skin health, but intense exercise without protection can harm it.
January 2024 in “Brazilian Journal of Veterinary Pathology” The horse had a rare disease causing weight loss and skin issues, leading to euthanasia due to poor treatment options.
September 2024 in “Actas Dermo-Sifiliográficas” Trichodynia is a painful scalp condition linked to hair loss and mental health issues, with limited treatment options.
61 citations
,
April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
46 citations
,
January 2020 in “Research” Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.
35 citations
,
November 2024 in “Gels” Hydrogel microneedles offer a painless, effective way to treat skin disorders.
32 citations
,
February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.
22 citations
,
November 2023 in “Molecules” Smart microneedles can deliver drugs painlessly and accurately for diseases like diabetes and tumors.
1 citations
,
September 2025 in “Physiologia” Ovalbumin–aluminum sensitization causes increased pain sensitivity and nerve changes in mice.
1 citations
,
October 2012 in “QJM” A 47-year-old man's eyelid swelling didn't improve with basic treatments, so a biopsy was needed.
13 citations
,
June 2019 in “Case reports in dermatology” Fat injections in the face can cause hair loss.