44 citations
,
February 2017 in “Journal of the American Academy of Dermatology” Lichen planopilaris (LPP) is linked to androgen excess, while frontal fibrosing alopecia (FFA) is linked to androgen deficiency.
Poly-L-lactic acid injections can cause hair loss and skin issues.
LGF injections may improve early Peyronie's disease by reducing penile curvature and plaque size.
23 citations
,
January 2010 in “Journal of The American Academy of Dermatology” Effective treatments for lichen planopilaris are unclear due to inconsistent results and a lack of strong research evidence.
February 2023 in “Journal of dermatology” The first Japanese case of a genetic hair disorder caused by specific mutations in the LIPH gene was identified.
10 citations
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June 2019 in “Case reports in dermatology” LALPS causes non-scarring hair loss along the Blaschko line, with unique trichoscopic findings.
July 2025 in “Cell & Bioscience” Specific immune cells and pathways contribute to hair follicle inflammation and hair loss, suggesting potential treatments for lichen planopilaris.
110 citations
,
January 2014 in “Journal of Controlled Release” Phospholipid-coated nanoparticles penetrate hair follicles better than others, especially in pig ears.
January 2026 in “Case Reports in Dermatological Medicine” Lichen Planus in siblings may be influenced by genetics and environment.
October 2024 in “Skin Appendage Disorders” Both environmental and genetic factors contribute to Lichen Planopilaris.
8 citations
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January 2019 in “Journal of cosmetic dermatology” Modified phenol peels effectively reduced stubborn skin pigmentation in patients with Lichen Planus Pigmentosus.
December 2024 in “Skin Appendage Disorders” More rigorous and diverse research is needed to improve diagnosis and treatment of Lichen Planopilaris.
September 2024 in “Skin Research and Technology” AFM can help diagnose lichen planopilaris by identifying specific hair structure changes.
May 2009 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” PPARgamma is crucial for healthy hair follicles, and its loss causes scarring alopecia.
1 citations
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April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Oral tofacitinib significantly improves lichen planopilaris symptoms without adverse effects.
August 2025 in “BMC Pharmacology and Toxicology” The LTF gene may help predict and manage nonspecific orbital inflammation.
May 2026 in “Scientific Reports” Overexpression of LRIG3 in skin causes hair loss.
October 2021 in “The Egyptian Journal of Hospital Medicine” Platelet-rich plasma is a safe and effective treatment for oral lichen planus.
October 2025 in “Italian Journal of Dermatology and Venereology” Lichen planopilaris is rare, mostly affects older women, and is often linked to autoimmune diseases like lupus.
Patients with lichen planopilaris have a higher risk of heart disease.
1 citations
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December 2024 in “Archives of Iranian Medicine” Tofacitinib may help treat Lichen Planopilaris, but more research is needed.
April 2016 in “Journal of Investigative Dermatology” Full thickness wounds on Lanyu pigs' skin resulted in abnormal skin structure and function due to changes in molecular expression patterns.
19 citations
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April 2018 in “International Journal of Dermatology” People with Lichen Planopilaris are more likely to have autoimmune diseases, especially Systemic Lupus Erythematosus, and less likely to have diabetes and some other common conditions.
3 citations
,
December 2023 in “International Journal of Nanomedicine” Repaglinide-loaded liponiosomal hybrids improve blood sugar control and insulin release better than regular Repaglinide.
3 citations
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May 2022 in “Clinical and experimental dermatology” Drugs targeting EMT molecules show promise for treating lichen planopilaris.
January 2022 in “Clinical Cases in Dermatology” A woman has a permanent hair loss condition treated with steroids and new medicines, but hair might not regrow.
24 citations
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December 2018 in “Life sciences” Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
22 citations
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April 2013 in “International Journal of Dermatology” Frontal fibrosing alopecia can occur with lichen planus pigmentosus, needing careful diagnosis and treatment.
July 1999 in “Journal of the American Academy of Dermatology”
March 2026 in “Dermatology Reports” FFA has higher long-term remission rates than LPP.