24 citations
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January 2014 in “PubMed” Imiquimod cream 5% effectively treated generalized discoid lupus erythematosus.
23 citations
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July 2015 in “Encyclopedia of Life Sciences” Systemic lupus erythematosus is a chronic disease causing inflammation and various symptoms, mainly in young women, treated with anti-inflammatory and immunosuppressive drugs.
23 citations
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December 1990 in “PubMed” SLE should be considered in horses with immune-related skin issues.
20 citations
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June 2021 in “British Journal of Dermatology” Use antimalarials like hydroxychloroquine for cutaneous lupus, avoid herbal supplements, and focus on lifestyle changes like sun protection.
20 citations
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October 2016 in “Veterinary dermatology” Dogs with generalized discoid lupus erythematosus have similar symptoms to humans and need continuous treatment.
19 citations
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May 2009 in “Pediatric Dermatology” A 5-year-old girl's scalp scarring and hair loss from lupus improved with specific medications.
19 citations
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January 2001 in “Internal Medicine” Protein-losing enteropathy worsened with lupus symptoms but improved with prednisolone.
18 citations
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July 2016 in “British Journal of Dermatology” Cutaneous lupus erythematosus greatly reduces patients' quality of life.
18 citations
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January 2016 in “Journal of Clinical Medicine Research” A woman with lupus and severe nerve damage improved with specific treatments.
16 citations
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January 2020 in “Annals of the rheumatic diseases” Baricitinib might help treat hair loss in lupus patients, but more research is needed.
16 citations
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August 2017 in “Lupus” Chronic cutaneous lupus erythematosus should be considered when acne treatments don't work.
16 citations
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June 2017 in “JAMA Dermatology” Thalidomide works best for skin lupus not helped by antimalarials, but has many side effects; other treatments are less effective, especially if patients also have systemic lupus.
16 citations
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April 2006 in “Pediatrics International” High-dose mizoribine effectively controls symptoms in adolescents with lupus while reducing steroid use, with manageable side effects.
15 citations
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June 2020 in “Journal of the American Academy of Dermatology” Shiny white structures in trichoscopy can indicate long-standing discoid lupus erythematosus alopecia.
15 citations
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March 2008 in “The Journal of Dermatology” Topical squaric acid dibutylester worsened discoid lupus erythematosus in a patient.
14 citations
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May 2009 in “Journal of the American Academy of Dermatology” The patient's scalp lesions stabilized with a combination of treatments after initial therapies failed.
12 citations
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January 2017 in “Skin appendage disorders” Two patients with skin lupus were mistakenly thought to have a different scalp condition but improved with lupus treatment.
12 citations
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July 2015 in “Tissue Antigens” The A allele of the C2 gene increases the risk of lupus, while the G allele may protect against it.
11 citations
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June 2015 in “Scientific Reports” The mtDNA N haplogroup is linked to a higher risk of late-onset lupus and specific symptoms in Han Chinese women.
11 citations
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February 2012 in “Pediatrics in Review” Early and aggressive treatment with individualized care plans is crucial for managing pediatric systemic lupus erythematosus.
11 citations
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August 1948 in “Journal of Investigative Dermatology” Calcium pantothenate therapy improved symptoms of discoid lupus erythematosus without side effects.
10 citations
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January 1994 in “Annals of Internal Medicine” CD4+ lymphocytopenia can occur in patients with systemic lupus erythematosus.
9 citations
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February 2011 in “Biologics: Targets & Therapy” Topical calcineurin inhibitors, especially 0.1% tacrolimus ointment, are effective and well-tolerated for treating cutaneous lupus erythematosus but require more research for standard treatment guidelines.
8 citations
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February 2006 in “Canadian Medical Association Journal” A woman with lupus and antiphospholipid syndrome had bone damage, showing the need for careful treatment.
8 citations
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June 1982 in “Journal of adolescent health care” Teenage girls with Lupus often struggle with the disease's impact on their looks, which may lead them to change their medication without a doctor's advice.
7 citations
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June 2018 in “Archives of Rheumatology” A woman with lupus developed rare skin growths that went away on their own.
6 citations
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April 2021 in “Frontiers in Immunology” A patient with lupus and long-term hair loss saw significant hair regrowth after using the drug tofacitinib.
6 citations
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April 2020 in “Cureus” A woman with both TLE and SLE improved with hydroxychloroquine treatment.
6 citations
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March 2005 in “The Journal of Dermatology” Radiation therapy can worsen Discoid Lupus Erythematosus.
5 citations
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May 2022 in “International Journal of Surgery Case Reports” Pericardiocentesis and immunosuppressants effectively treat cardiac tamponade in pregnant women with SLE.