May 2025 in “International Journal of Trichology” A rare case of hair loss was linked to breast cancer spreading to the scalp, but treatment was effective.
May 2024 in “Journal of Advanced Research” Communication between blood vessel and hair follicle cells decreases with age, affecting hair growth and blood vessel formation.
May 2023 in “Journal of Cosmetic Dermatology” Being overweight can cause or worsen skin problems in children, some more common in darker skin, and is often linked to insulin resistance.
559 citations
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October 2020 in “Frontiers in Molecular Biosciences” Solid lipid nanoparticles are promising for safe and effective drug delivery but need more research for clinical use.
305 citations
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March 2008 in “AJP Endocrinology and Metabolism” SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.
222 citations
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January 2003 in “Critical Reviews in Therapeutic Drug Carrier Systems” Ethosomes can safely and effectively deliver various drugs deep into the skin.
164 citations
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December 2000 in “Journal of Dermatological Science” Targeting blood vessels may help treat skin diseases.
154 citations
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November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
138 citations
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June 2004 in “Journal of Investigative Dermatology” Involucrin gene expression is controlled by specific proteins and signaling pathways.
135 citations
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December 2006 in “PLoS Medicine” Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.
134 citations
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July 2020 in “Experimental dermatology” Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
133 citations
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July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
106 citations
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August 2021 in “Pharmaceuticals” Extracellular vesicles help heal skin wounds and could be used for better treatments.
100 citations
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May 2006 in “American Journal Of Pathology” Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.
88 citations
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August 2019 in “Frontiers in immunology” Tyrosine kinases are important in skin autoimmune diseases and could be targets for new treatments.
75 citations
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February 2017 in “Aging” SkQ1 antioxidant improved health and lifespan in mice.
74 citations
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October 2023 in “Nature Reviews Molecular Cell Biology” 72 citations
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March 2023 in “Biomolecules” Dupilumab effectively treats various inflammatory skin diseases beyond its initial use for atopic dermatitis.
56 citations
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November 2003 in “Journal of Investigative Dermatology” MMP-19 may worsen skin diseases by affecting skin growth and inflammation.
53 citations
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January 2013 in “Journal of toxicologic pathology” The project created a standardized system for classifying skin lesions in lab rats and mice.
52 citations
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January 2023 in “Annual Review of Immunology” Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.
52 citations
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January 2003 in “Journal of Investigative Dermatology” Thrombospondin-1 is crucial for hair follicle regression and reduced blood vessel growth during the catagen phase.
51 citations
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December 2017 in “Skin Appendage Disorders” Stress may trigger hair loss by affecting immune protection in hair follicles.
49 citations
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February 2025 in “Science Advances” Biomimetic synthetic vesicles could improve precision medicine by combining natural and synthetic benefits.
49 citations
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November 2021 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
42 citations
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June 2021 in “Pharmaceutics” 3D printing can make microneedles for drug delivery faster and cheaper.
35 citations
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January 2006 in “Dermatology Online Journal” Lipedematous scalp may be underdiagnosed and doesn't improve with finasteride.
31 citations
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August 2022 in “Frontiers in Oncology” Photobiomodulation therapy helps manage cancer treatment side effects but needs more research for optimization.
29 citations
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December 2021 in “Pharmaceutics” Phospholipid soft vesicles improve topical drug delivery for better skin condition treatments.
29 citations
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September 2018 in “Journal of the American Heart Association” EP 2 receptor is essential for heart repair by helping macrophages work properly.