Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.
15 citations
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October 2012 in “InTech eBooks” Niosomes are a promising and effective way to deliver drugs through the skin.
4 citations
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July 2025 in “International Journal of Nanomedicine” Nano-quercetin improves quercetin's effectiveness in treating diseases but faces challenges in safety and production.
January 2026 in “International Journal of Applied Pharmaceutics” Nanoparticle-embedded microneedles improve drug delivery through the skin but face challenges in stability and safety.
June 2026 in “Discover Nano” Lipid nanocarriers could effectively promote hair regrowth with fewer side effects.
August 2025 in “MedComm – Biomaterials and Applications” Liposomal delivery systems improve drug absorption through the skin, offering potential for better treatments.
451 citations
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March 2005 in “Endocrine Reviews” The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
56 citations
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October 2007 in “Journal of Biological Chemistry” Cathepsin L is essential for heart health and its absence causes heart problems and hair loss.
1 citations
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November 2011 in “British journal of pharmacology” Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
October 2020 in “Journal of Pharmaceutical Sciences” Topical finasteride with EGCG or TA improves drug release and dermal uptake, potentially treating hair loss effectively.
November 2023 in “ACS Omega” New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
2 citations
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April 2009 in “Bulletin of Experimental Biology and Medicine” Flamena, a liposomal mix, helps skin heal better after a chemical burn.
47 citations
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September 2015 in “Journal of Drug Delivery Science and Technology” Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.
10 citations
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September 2023 in “Metabolites” Iron is crucial for skin health, with specific proteins recycling it to support skin functions and prevent its release.
23 citations
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March 2021 in “Gels” Microemulsions can improve minoxidil delivery and effectiveness for hair loss treatment.
March 2023 in “Scientific reports” Hair growth-related cells need the enzyme SCD1 to help maintain the area that supports hair growth.
7 citations
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January 2024 in “Regenerative Biomaterials” The new dressing improves chronic wound healing by preserving and releasing growth factors effectively.
1 citations
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July 2025 in “Chemosensors” A new wearable system improves wound healing by monitoring infections and delivering precise treatment.
12 citations
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January 2018 in “Journal of Drug Delivery Science and Technology” The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
7 citations
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October 2024 in “Cells” Autophagy is essential for proper skin cell development and function.
13 citations
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November 2022 in “Future Journal of Pharmaceutical Sciences” Liposome-based cosmeceuticals improve treatment effectiveness for skin and hair conditions.
18 citations
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October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
344 citations
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May 2018 in “EMBO journal” Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.
122 citations
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December 2022 in “International Journal of Molecular Sciences” Nanoparticles improve skin treatment but need more research on safety and effectiveness.
1 citations
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July 2025 in “Advanced Materials” The zinc-coordinated nanogel therapy speeds up wound healing after pancreas surgery by balancing metabolism and fighting bacteria.
13 citations
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September 2023 in “Molecules” Liposomal coffee berry extract improves skin elasticity and reduces melanin better than regular extract.
36 citations
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August 2022 in “Molecular Therapy — Nucleic Acids” Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
9 citations
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June 2024 in “Cell Reports” Hair follicles play a crucial role in regulating skin barrier function.
4 citations
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October 2024 in “International Journal of Molecular Sciences” GCN reduces lung inflammation and damage from air pollution in mice.
January 2025 in “International Journal of Research and Innovation in Applied Science” The developed glycerosome gel improves minoxidil delivery for better alopecia treatment.