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Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Accurate diagnosis of RDEB-mitis in older adults is crucial for proper management without immunosuppressants.

Patients with acne and insulin resistance have different blood metabolites compared to those with only acne, which could help in diagnosis and treatment.

DRDE-07 shows promise for treating skin diseases due to its favorable properties.

Sebaceous lipids are crucial for keeping skin and eyes healthy in mice.

The new micelle formulation delivers acne treatment more effectively and safely than current gels.

The study created a mouse model to mimic degenerative diseases for testing tissue repair and new therapies.

CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.

Lymphoid-specific helicase (Lsh) is crucial for skin growth, change, and healing after injury.

Standardized guidelines are needed to improve drug-loaded extracellular vesicle purification.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Cinnamic acid in hydrogels can effectively fight fungi but spreads less than in solution.

A new mouse mutation causes skin and hair defects due to a gene change.

The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.

Vepdegestrant may become the first FDA-approved PROTAC degrader, marking a new era in drug development.

Paeonol-loaded gels may help reduce inflammation and skin damage in atopic dermatitis.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Targeting cellular senescence may improve skin aging and disorders.

Stem cell niche exit in C. elegans is influenced by Sh1 cell membrane protrusions.

Follicular mucinosis causes significant damage to hair follicle cells.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Interest in using microorganisms to reduce ocean pollution is growing.

Some brain cancer cells avoid immune system detection, and certain treatments could target this to slow their growth; also, certain fat cell precursors help regenerate hair and skin after injury.

Skin tumors with CYLD cutaneous syndrome show more NF-κB activity and less organized collagen.

Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.

Skin tumor cells in patients with tuberous sclerosis have higher levels of a protein called cathepsin B.

Niosomes are a promising and effective way to deliver drugs through the skin.

Activating mitophagy may help manage a key immune response involved in the hair loss condition alopecia areata.