55 citations
,
November 2019 in “Cellular and Molecular Gastroenterology and Hepatology” Biotin may help treat inflammatory bowel disease by reducing inflammation and improving gut health.
4 citations
,
July 2019 in “Clinical and experimental dermatology” Early diagnosis and biotin treatment are crucial for infants with biotinidase deficiency to prevent severe complications.
November 2025 in “Journal of Saidu Medical College Swat” Biotinidase deficiency can mimic other conditions, making early diagnosis and treatment crucial to prevent lasting issues.
Biotin does not significantly help with hair growth.
1 citations
,
January 1999 in “Proceedings of the British Society of Animal Science” Biotin helps maintain hair follicle growth by affecting cell death and survival signals.
August 2021 in “Benha Journal of Applied Sciences” Biotin supplements significantly improve hair loss in people with telegon effluvium who lack biotin.
October 2023 in “International Journal of Cosmetic Science” WS Biotin, a new form of D-Biotin, improves water solubility and shows potential for hair and skin care without being toxic at low levels.
29 citations
,
July 1996 in “Acta Paediatrica” Biotin should be added to Japanese amino acid formula to prevent deficiency.
4 citations
,
March 2021 in “Experimental dermatology” Minoxidil increases nail growth more than biotin.
May 2025 in “Health Science Reports” Serum WS Biotin significantly reduces hair shedding and improves hair thickness.
78 citations
,
January 2017 in “Skin appendage disorders” Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.
October 2019 in “UNESP Institutional Repository (São Paulo State University)” Minoxidil is more effective than biotin for increasing nail growth rate.
September 2020 in “Benha Journal of Applied Sciences” Patients with Alopecia Areata have lower levels of zinc and biotin than healthy individuals.
5 citations
,
March 2021 in “International Journal of Dermatology” Biotin supplementation during isotretinoin treatment for acne may help maintain skin hydration and improve hair growth.
11 citations
,
February 2019 in “Journal of Cosmetic Dermatology” Low zinc and biotin levels linked to male hair loss; supplements may help.
24 citations
,
May 2017 in “PubMed” Biotin supplements for hair improvement are popular without scientific proof of effectiveness.
4 citations
,
December 1995 in “Archives of Dermatological Research”
16 citations
,
January 2008 in “Acta dermato-venereologica” Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.
September 2024 in “Meditsinskiy sovet = Medical Council” Biotin effectively treats hair loss, skin, and nail issues without overdose risk.
June 1987 in “Pediatric Neurology Briefs” Biotinidase deficiency can cause symptoms like sleepiness, hair loss, and seizures.
1 citations
,
July 2022 in “Dermatologic Therapy” Both brands of biotin and dexpanthenol injections improved hair loss, with Bayer also increasing the ratio of thick to thin hairs.
11 citations
,
January 1989 in “PubMed” Biotin improved fur and skin conditions in most dogs.
January 2019 in “Kocaeli tıp dergisi” People with chronic hair loss may have a higher chance of Vitamin B12 deficiency.
4 citations
,
March 2020 in “JAAD Case Reports” Vitamin B12 deficiency can cause darkening of all nails.
27 citations
,
July 1946 in “The journal of nutrition/The Journal of nutrition” Biotin and inositol are crucial for pig health and growth.
49 citations
,
April 2007 in “Pediatric Dermatology” Biotin improved hair appearance in uncombable hair syndrome but didn't change hair structure.
April 2024 in “International Journal of Advanced Research” Vitamin B12 deficiency is linked to hair loss and skin pigmentation changes.
13 citations
,
May 2012 in “Cutaneous and ocular toxicology” Alopecia areata is not linked to vitamin B12 deficiency.
36 citations
,
October 2008 in “European journal of paediatric neurology” Valproic acid treatment may cause temporary hair loss due to reduced zinc and biotinidase levels, which tend to normalize after 6 months.
5 citations
,
December 1942 in “Journal of the American Medical Association” Choline and biotin are important for liver health and preventing certain deficiencies in animals, and more research is needed to understand their benefits in humans.