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research A multi-omic single-cell landscape of perinatal mouse skin maps lineage specification and reveals shared dynamics in human fetal skin
Mouse and human skin development share similar fibroblast timelines.
research Lysophosphatidic acid and signaling in sensory neurons
Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.
research 364 Mechanical forces of human dermal fibroblasts significantly decrease with age
Skin cell strength decreases significantly as we age.
research The cell membrane complex: Three related but different cellular cohesion components of mammalian hair fibers
The cell membrane complex in mammalian hair has three distinct types with different structures and chemical properties.
research 574 Murine sebaceous gland homeostasis requires intact cutaneous innervation in a hair cycle-dependent context
Mouse skin glands need healthy nerves to grow properly during hair growth phases.
research Multimodal Evidence of Mesostructured Calcium Fatty Acid Deposits in Human Hair and Their Role on Hair Properties
Calcium fatty acid deposits found in human hair can change its appearance and feel.
research Response of the Skin of Mice to Methyl Ether of Vitamin A and Vitamin A Palmitate1
research Constitutive Internalization of the Leucine-rich G Protein-coupled Receptor-5 (LGR5) to the Trans-Golgi Network
LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.
research Electro-optical imaging of F-actin and endoplasmic reticulum in living and fixed plant cells.
Imaging living plant cells shows dynamic changes in actin and endoplasmic reticulum linked to root hair growth.
research A novel fracture lattice in spiny mouse skin facilitates tissue autotomy and regeneration
Spiny mice have a unique skin structure that helps them heal and regenerate quickly.
research Upregulation of genes orchestrating keratinocyte differentiation, including the novel marker gene ID2, by contact sensitizers in human bulge‐derived keratinocytes
The ID2 gene can help distinguish between sensitizers and irritants in skin cells.
research Minoxidil Stimulates Elastin Expression in Aortic Smooth Muscle Cells
research 442 Deciphering the role of keloid fibroblasts in itch
Keloid fibroblasts cause itch and pain by releasing more histamine.
research Stem Cells Sheltered from Air-Raids Repair Airways
Myoepithelial cells can repair airways after severe injury.
research Induction of meibocyte differentiation by three-dimensional, matrigel culture of immortalized human meibomian gland epithelial cells to form acinar organoids
research Functional characterization of OR51B5 and OR1G1 in human lung epithelial cells as potential drug targets for non-type 2 lung diseases
Blocking certain receptors in the lungs might help treat a specific type of asthma.
research THE HUMAN HAIR FOLLICLE PULSATING BIOMAGNETIC FIELD REACH AS POSSIBLE ADDITIONAL FACTOR IN MIGRAINE HEADACHES A BIOPHYSICS BASED HYPOTHESIS
Human hair follicles' biomagnetic fields might contribute to migraines.
research Morpho-Regulation of Ectodermal Organs
Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
research LB1059 Neuromediators associated with neurogenic skin inflammation promote M2 differentiation of macrophages in human skin ex vivo
Certain substances can help skin cells become anti-inflammatory, aiding in tissue repair.
research Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
research Bioelectric medicine: unveiling the therapeutic potential of micro-current stimulation
research Human Scalp Dermal Papilla and Fibrous Sheath Cells have a different expression profile of Matrix Metalloproteinases in vitro when compared to Scalp Dermal Fibroblasts
Scalp dermal papilla and fibrous sheath cells have different MMP expression than scalp dermal fibroblasts.
research Cell surface receptor kinase FERONIA linked to nutrient sensor TORC signaling controls root hair growth at low temperature linked to low nitrate inArabidopsis thaliana
A protein called FERONIA helps control root hair growth in response to cold and low nitrogen by activating nutrient-sensing pathways in a plant called Arabidopsis.
research Pulling force deforms hair follicle root sheath nuclei and surrounding dermal collagen matrix differently at infundibulum, isthmus and suprabulbar regions
Hair follicles respond differently to pulling forces in various regions.
research Dynamic immunomodulatory nanoarchitectonics: Rewiring tissue regenerative microenvironment via intelligent regulation
Nanotechnology can improve tissue healing by controlling immune responses.
research Label-Free Automated Cell Tracking: Analysis of the Role of E-cadherin Expression in Collective Electrotaxis
E-cadherin is important for cell movement in electric fields, and the new tracking method works well.
research Adipocytic Progenitor Cells Give Rise to Pathogenic Myofibroblasts: Adipocyte-to-Mesenchymal Transition and Its Emerging Role in Fibrosis in Multiple Organs
Targeting adipocyte-to-mesenchymal transition could help treat fibrosis.
research Unraveling the molecular basis of ROS-mediated cell wall biomechanics during Arabidopsis root hair cell growth
ROS influences the growth and structure of Arabidopsis root hairs.
research Skin aging as a mechanical phenomenon: The main weak links
Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.