research Physical and mechanical cues affecting biomaterial-mediated plasmid DNA delivery: insights into non-viral delivery systems
Biomaterials can improve non-viral gene delivery by enhancing DNA uptake and reducing toxicity.
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780-810 / 1000+ resultsresearch Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken
Gene regulation evolved differently in mouse and chicken skin, but remained stable in their trunks.
research Zinc deficiency triggers hearing loss by reducing ribbon synapses of inner hair cells in CBA/N mice
Lack of zinc can cause hearing loss by damaging important parts of inner ear cells in mice.
research PIK3CA gain-of-function mutation in Schwann cells leads to severe neuropathy and aerobic glycolysis through a non-cell autonomous effect
A PIK3CA mutation in Schwann cells causes severe nerve damage and increased glycolysis, but early treatment can help.
research Long-term staining of live Merkel cells with FM dyes
FM dyes effectively stain Merkel cells for long-term observation.
research An in vivo method for the detection of somatic mutations at the cellular level in mice
A new method can detect mutations in mice by observing changes in hair follicle cells.
research Matrix Metalloproteinase-9 Is Involved in the Regulation of Hair Canal Formation
MMP-9 is essential for proper hair canal formation.
research 1430 Modeling the onset of senescence associated secretory phenotype predicts therapeutic targets
The research found that blocking a gene called NEMO can potentially prevent harmful effects of aging at the cellular level.
research Allergic contact dermatitis from minoxidil
Some people using minoxidil for hair loss developed an allergic skin reaction, often related to an ingredient that helps minoxidil work better.
research Bridging Personal and Population in Excitability Diseases: Will Studies of Rare Diseases Bring Generalizable Mechanisms From Monogenic Channelopathies?
Studying rare genetic disorders can help us understand and treat common diseases better.
research 0877 Activated wound phenotype and microbial dysbiosis are driven by AhR suppression in hidradenitis suppurativa tunnels
Reduced AhR signaling in HS tunnels leads to persistent inflammation and microbial imbalance.
research Mice Expressing a Mutant Krt75 (K6hf) Allele Develop Hair and Nail Defects Resembling Pachyonychia Congenita
research Bioinspired Strategies for Wound Regeneration
Combining biochemical, immune, and mechanical signals can improve skin regeneration.
research A TA/Cu2+ Nanoparticle Enhanced Carboxymethyl Chitosan-Based Hydrogel Dressing with Antioxidant Properties and Promoting Wound Healing
The hydrogel is safe, reduces oxidation, and helps heal wounds effectively.
research Machine learning for nanozyme development in anti‐inflammatory applications
Rational design strategies are crucial for developing effective nanozymes for anti-inflammatory uses.
research Modulation der Hitzesensitivität im Prostatakarzinom in vitro: Der Einfluss der Androgenachse
Androgen-modulating drugs do not significantly change the heat sensitivity of prostate cancer cells.
research Epigenetic orchestration of RNA m6A methylation in wound healing and post-wound events
m6A methylation is crucial for proper wound healing and tissue repair.
research Induction of Hard Keratin Expression in Non-Nail-Matrical Keratinocytes by Nail-Matrical Fibroblasts through Epithelial-Mesenchymal Interactions
Nail-matrical fibroblasts can make non-nail cells produce hard keratin, useful for nail repair.
research Pathogenetic Characteristics of Mesenchymal Stem Cells in Hidradenitis Suppurativa
Mesenchymal stem cells in people with Hidradenitis Suppurativa are more inflammatory, possibly contributing to the disease.
research Autonomous wearable sensing enabled by capillary microfluidics: a review
Capillary microfluidic wearables are promising for non-invasive health monitoring through sweat and saliva.
research Nucleus‐specific modulation of phasic and tonic inhibition by endogenous neurosteroidogenesis in the murine thalamus
Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.
research Small animal models of thermal injury
research 371 THE EFFECTIVENESS OF BIO-REGULATORY MAGNETO-LASER THERAPY OF CHRONIC PELVIC PAIN SYNDROME/CHRONIC PROSTATITIS IMA
research Single-cell transcriptomics reveals hair growth retardation mediated by aberrant connective tissue sheath contraction in male androgenetic alopecia
Inhibiting connective tissue sheath contraction may improve hair growth in male pattern baldness.
research Dual‐flow‐RootChip reveals local adaptations of roots towards environmental asymmetry at the physiological and genetic levels
Roots adapt to uneven environments by changing growth and gene expression.
research Electrospun Nanofibers for Biomedical, Sensing, and Energy Harvesting Functions
Electrospun nanofibers are promising for medical, sensing, and energy uses, especially with 3D printing.
research Pathogenesis and management of TRPV3-related Olmsted syndrome
EGFR and mTOR inhibitors may help manage Olmsted syndrome symptoms.
research An intergenerational androgenic mechanism of female intrasexual competition in the cooperatively breeding meerkat
Androgens in female meerkats influence aggression and dominance, affecting social dynamics and offspring behavior.
research Accessing Properties of Molecular Compounds Involved in Cellular Metabolic Processes with Electron Paramagnetic Resonance, Raman Spectroscopy, and Differential Scanning Calorimetry
These methods help understand cell structures and reactions.
research Sulfotransferase activity in plucked hair follicles predicts response to topical minoxidil in the treatment of female androgenetic alopecia
Sulfotransferase in hair follicles helps predict how well minoxidil works for female hair loss.