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research Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis

47 citations , September 2012 in “Human molecular genetics online/Human molecular genetics”

Folliculin deficiency causes problems with cell division and positioning due to disrupted RhoA signaling and interaction with p0071.

research Effect of Fibroblast Growth Factor 10 and an Interacting Non-Coding RNA on Secondary Hair Follicle Dermal Papilla Cells in Cashmere Goats’ Follicle Development Assessed by Whole-Transcriptome Sequencing Technology

2 citations , July 2023 in “Animals”

FGF10 and non-coding RNAs are important for cashmere goat hair follicle development.

research Tfap2b specifies an embryonic melanocyte stem cell that retains adult multi-fate potential

June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.

research 564 Subpopulations of dermal fibroblasts produce distinct extracellular matrices

August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

Different types of skin cells create unique support structures that can affect skin cell growth and could help in skin repair.

research MicroRNA-21 in Skin Fibrosis: Potential for Diagnosis and Treatment

32 citations , July 2017 in “Molecular diagnosis & therapy”

MicroRNA-21 could help diagnose and treat skin fibrosis.

research Harnessing the Biomimetic Effect of Macromolecular Crowding in the Cell-Derived Model of Clubfoot Fibrosis

6 citations , August 2024 in “Biomacromolecules”

The model helps test drugs for clubfoot fibrosis by mimicking cell environments and shows minoxidil reduces harmful collagen links.

research The Significance of NOTCH Pathway in the Development of Fibrosis in Systemic Sclerosis

25 citations , January 2019 in “Annals of Dermatology”

Blocking the NOTCH pathway can prevent fibrosis in systemic sclerosis.

research Embryonic development of hair follicle pluripotent stem (hfPS) cells

11 citations , June 2010 in “Medical Molecular Morphology”

research LncRNA018392 promotes the proliferation of Liaoning cashmere goat skin fibroblasts by upregulating CSF1R through binding to SPI1

3 citations , August 2024 in “Molecular Biology Reports”

LncRNA018392 helps goat skin cells grow by increasing CSF1R.

research FGF22 Secreted by Hair Papilla Cells Regulates Hair Follicle Stem Cell Proliferation and Differentiation

November 2025 in “Biomolecules”

FGF22 helps hair follicle stem cells grow and develop.

research Mechanisms of Submucosal Gland Morphogenesis in the Airway

9 citations , December 2002 in “Novartis Foundation Symposium”

LEF1 is essential for the development of airway glands and is regulated by the Wnt/ß-catenin pathway.

research Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

1 citations , March 2022 in “Journal of biological chemistry/The Journal of biological chemistry”

Removing a specific gene in certain skin cells causes hair loss in mice by disrupting hair follicle development.

research LHX2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth

43 citations , January 2016 in “Development”

LHX2 is essential for hair follicle development, controlled by NF-κB and TGFβ2 signaling.

research Extracellular vesicles derived from embryonic day 13 fetal mouse dermal fibroblasts exhibit potential antifibrotic activity

April 2026 in “Research Square”

E13 fetal mouse fibroblast vesicles may help reduce scarring.

research Fibroblast Growth Factors in Epithelial Homeostasis and Repair

December 2016

Fibroblast Growth Factors (FGFs) help maintain and repair skin tissues, which is important for preventing diseases like inflammation, fibrosis, and cancer.

research Regeneration of fat cells from myofibroblasts during wound healing

408 citations , January 2017 in “Science”

Some wound-healing cells can turn into fat cells around new hair growth in mice.

research Human hair follicle stem cell differentiation into contractile smooth muscle cells is induced by transforming growth factor-β1 and platelet-derived growth factor BB

19 citations , September 2013 in “Molecular Medicine Reports”

Human hair follicle stem cells can become smooth muscle cells using specific growth factors.

research Single‐cell RNA sequencing highlights the role of proinflammatory fibroblasts, vascular endothelial cells, and immune cells in the keloid immune microenvironment

6 citations , October 2024 in “International Journal of Dermatology”

Proinflammatory fibroblasts and vascular endothelial cells are key in keloid development.

research LncRNA018392 promotes proliferation of Liaoning cashmere goat skin fibroblasts through up-regulation of CSF1R by binding to SPI1

April 2023 in “Research Square (Research Square)”

A specific RNA helps increase the growth of skin cells in Liaoning cashmere goats by working with a protein to boost a growth-related gene.

research Human keratin hydrogels support fibroblast attachment and proliferation in vitro

143 citations , January 2012 in “Cell and Tissue Research”

research Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated with Upregulation of Cyclin D1 and Downregulation of p16

83 citations , October 2016 in “Stem Cells and Development”

Epidermal growth factor helps hair stem cells grow by activating specific cell pathways.

research Dermal EZH2 simultaneously orchestrates dermal differentiation and epidermal proliferation during murine skin development

November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Dermal EZH2 controls skin cell growth and differentiation in mice.

research FOXE1, A New Transcriptional Target of GLI2 Is Expressed in Human Epidermis and Basal Cell Carcinoma

92 citations , May 2004 in “Journal of Investigative Dermatology”

research Epidermal growth factor and transferrin receptor expression in human embryonic and fetal epidermal cells

10 citations , December 1990 in “Archives of Dermatological Research”

research Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation induced tissue damage

1 citations , June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

UV exposure harms skin by causing fibroblast loss, but T cells help fibroblast survival.

research GENOTYPE ? PHENOTYPE CORRELATIONS IN CUTANEOUS MELANOMA PATIENTS CARRIER OF THE MITF p.E318K PATHOGENIC VARIANT

May 2019 in “CINECA IRIS Institutial Research Information System (University of Genoa)”

MITF+ melanoma patients are more likely to have multiple melanomas and unique skin patterns.

research Tissue-engineered dermal substitutes constructed by human embryonic stem cell-derived fibroblasts facilitate the repair of skin wounds

March 2026 in “Frontiers in Bioengineering and Biotechnology”

Stem cell-derived fibroblasts can effectively repair skin wounds.

research Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization

24 citations , July 2017 in “Structure”

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

research Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

475 citations , October 2006 in “Proceedings of the National Academy of Sciences”

Folliculin helps regulate energy and nutrient sensing, impacting Birt–Hogg–Dubé syndrome.

In Vitro Cultured Human-Derived HFMSCs Show Potential to Promote Wound Healing

research In vitro cultured human-derived HFMSCs have shown the potential to promote wound

January 2026 in “China National GeneBank DataBase”

Human hair follicle stem cells can help heal wounds faster.

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