September 2023 in “Cureus” Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.
July 2023 in “International journal of trichology” Injectable platelet-rich fibrin may stop hair loss from Discoid lupus erythematosus.
89 citations
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June 2012 in “Anais Brasileiros de Dermatologia” Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.
1 citations
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March 2018 in “Cureus” Scrotal rejuvenation treats aging-related changes in men's scrotum using methods like medication, hair transplantation, and surgery.
December 2019 in “Medicina estética” Dermoscopy is underused in aesthetic medicine, but it increases diagnosis confidence; more training is needed.
December 2019 in “Medicina estética” Dermoscopy is underused in aesthetic medicine, but it increases diagnostic confidence, and professionals need more training.
401 citations
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January 2013 in “Postepy Dermatologii I Alergologii” The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
283 citations
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February 2011 in “Cell stem cell” COL17A1 is crucial for preventing hair graying and loss by supporting hair and pigment stem cells.
260 citations
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January 2020 in “Nature” Stress can cause hair to turn gray by depleting stem cells.
260 citations
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June 2011 in “Cell” Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
240 citations
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April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
210 citations
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May 2006 in “The FASEB journal” Oxidative stress causes hair to gray by damaging and killing pigment cells.
177 citations
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November 2002 in “British journal of dermatology/British journal of dermatology, Supplement” Transplantation is effective for stable leucoderma but not for progressive, widespread vitiligo vulgaris.
164 citations
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February 2010 in “Journal of Cell Science” Human dermal stem cells can become functional skin pigment cells.
146 citations
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May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.
105 citations
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April 2005 in “Cell” Hair graying happens because certain cells aren't maintained properly.
93 citations
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October 2006 in “The International Journal of Biochemistry & Cell Biology” Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
91 citations
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March 2011 in “Stem Cell Reviews and Reports” Human epidermal neural crest stem cells can become bone and skin pigment cells, making them useful for therapies.
86 citations
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August 2000 in “Pigment cell research” Melanocyte activity in hair follicles is linked to the hair growth cycle, being active in growth phases and inactive in rest phases.
85 citations
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July 2002 in “Pigment Cell Research” The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
69 citations
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January 1995 in “PubMed” Mouse melanocyte structure and function are influenced by genetics, hormones, and environmental factors.
68 citations
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March 2008 in “Experimental dermatology” The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
67 citations
,
November 2019 in “Nature Communications” Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
66 citations
,
December 2014 in “Nature Communications” Fibroblasts can be turned into melanocytes for potential skin treatments.
59 citations
,
April 2016 in “Cell Reports” EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
57 citations
,
April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
56 citations
,
November 1958 in “The Journal of Cell Biology” A unique skin cell similar to hair bulb melanocytes was identified, with better preservation using permanganate fixation.
55 citations
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December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Keratinocytes control how melanocytes work.
45 citations
,
April 2016 in “Journal of Dermatological Science” The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
43 citations
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October 2005 in “Molecular and cellular endocrinology” Hair melanocytes help the skin respond to stress and regulate hair pigmentation.