47 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Premature graying of hair may suggest health issues and currently lacks effective treatments.
15 citations
,
January 2017 in “Pigment International” Early hair graying is often inherited and influenced by genetics, environment, and lifestyle, but treatment options are limited.
3 citations
,
November 2022 in “Frontiers in Oncology” Melanin may help melanoma cells grow by aiding their metabolism.
28 citations
,
July 2005 in “International Journal of Dermatology” Vitiligo is caused by the immune system attacking skin pigment cells.
May 2019 in “Australasian Journal of Dermatology” New insights in skin conditions show a complex link between certain moles and melanoma, improved hair loss treatments, and the need to identify different types of lupus.
March 2009 in “Chinese Journal of Dermatology” Melanocytes in the outer root sheath are likely stem cells that grow fast but stay immature.
4 citations
,
May 2023 in “Pigment Cell & Melanoma Research” BMI1 is essential for preventing hair greying and maintaining hair color.
10 citations
,
May 2016 in “Journal of Dermatological Science” PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.
July 2026 in “Clinics in Dermatology” Topical melatonin may help protect and rejuvenate skin.
39 citations
,
December 2008 in “Clinics in Dermatology” Dermoscopy has improved skin cancer diagnosis and has expanding applications in dermatology, but requires staying updated with new research and techniques.
72 citations
,
November 1997 in “Clinics in dermatology” Vitiligo is a skin condition causing white patches, likely due to an autoimmune issue.
31 citations
,
November 2015 in “PloS one” Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
September 2022 in “Scientific Reports” Scalp melanoma is more common and easier to diagnose early in people with androgenetic alopecia due to sun damage.
35 citations
,
August 2009 in “Journal of the American Academy of Dermatology” Melanocytes might be targeted by the immune system in people with alopecia areata, but more research is needed.
April 2015 in “Experimental Dermatology” Melanoma risk tools need improvement, certain gene mutations cause skin diseases and could be treated by targeting those mutations, skin wrinkling may relate to lung aging due to genetic factors, and oxidative stress affects hair loss but can be reduced in low oxygen.
July 2022 in “European Journal of Dermatology” Brodalumab is more effective than ustekinumab in treating psoriasis.
4 citations
,
October 2012 in “Expert Review of Dermatology” Dermoscopy greatly improves melanoma diagnosis and reduces unneeded surgeries.
40 citations
,
November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Different melanocyte types in hair follicles either survive or die during the catagen phase.
March 2026 in “International Journal of Innovative Technologies in Social Science” Vitiligo is a systemic disease with psychological effects, and new treatments focus on personalized care.
10 citations
,
November 2009 in “Pigment cell & melanoma research” The document concludes that MGRN1 affects mouse fur color by interfering with a receptor's signaling, but its full role in the body is still unknown.
April 2026 in “The FASEB Journal” Exosomal miR-199a-3p from dermal papilla cells helps control hair color by affecting melanocytes.
May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Nicastrin deficiency may cause skin cell damage and pigmentation disorders in humans, similar to effects seen in fish.
May 2026 in “International Journal of Drug Delivery Technology” Accurate diagnosis of EFFC is crucial for effective counseling and cosmetic care.
1 citations
,
April 2008 in “Pigment Cell & Melanoma Research” Foxn1 is essential for hair pigmentation by directing pigment transfer to hair cells.
March 2007 in “International Journal of Cosmetic Science” Hair with more melanin resists weather damage better.
1 citations
,
May 2023 in “Cutis” Eating disorders can cause skin problems, which may help with early diagnosis and treatment.
July 2026 in “Current Issues in Molecular Biology” Plerixafor may help restore skin pigmentation safely.
22 citations
,
September 2008 in “International Journal of Dermatology” The case suggests a possible autoimmune link between lichen sclerosus and vitiligo.
3 citations
,
May 2011 in “Practice nursing” As skin ages, it gets thinner, paler, and more wrinkled, and protection and care like sunblock and moisturizers are important.
11 citations
,
May 2021 in “Journal of Cosmetic Dermatology” Platelet-rich plasma therapy could be an effective treatment for melasma with minimal side effects.