April 2026 in “npj Regenerative Medicine” Melanocyte stem cells in hair follicles are key to understanding and potentially preventing hair graying.
Multiphoton microscopy helps understand and improve vitiligo treatments by visualizing skin cell changes.
85 citations
,
July 2002 in “Pigment Cell Research” The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
24 citations
,
March 2018 in “Pigment Cell & Melanoma Research” The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.
2 citations
,
September 2009 in “Pigment Cell & Melanoma Research” Melanocytes in different body areas have evolved to perform specific functions based on their location.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found markers indicating that cells responsible for hair color are differentiating in specific areas of the hair follicle.
18 citations
,
August 2021 in “PLoS ONE” Melanocyte progenitor cells are found in human fat tissue and can become mature melanocytes, which may help treat skin issues.
5 citations
,
September 2018 in “Journal of Investigative Dermatology” Keratinocyte cytokines and genetic variations influence the development of moles and skin pigmentation.
January 2006 in “Linchuang pifuke zazhi” Stem cell factor and certain proteins help melanocytes from hair follicles move and attach better, aiding vitiligo repigmentation.
9 citations
,
July 2022 in “Cell reports” Sox2 controls hair color by affecting pigment production in hair follicles.
August 2023 in “Journal of Investigative Dermatology” Senescent melanocytes in nevus skin boost hair growth.
75 citations
,
January 1980 in “Journal of Investigative Dermatology” 27 citations
,
May 2024 in “Clinical and Translational Medicine” Melanocyte stem cells are vital for skin and hair color and have potential in treating skin disorders and cancer.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” BMP signaling controls hair growth and skin color.
60 citations
,
February 1997 in “Journal of Dermatological Science” Liposomes can safely and effectively deliver substances to mouse hair follicles, potentially useful for human hair treatments.
2 citations
,
September 2024 in “Animals” Key genes influence melanin in chicken muscles, affecting their value.
April 2016 in “Journal of Investigative Dermatology” Tumor cell adhesion is linked to higher risk of SLN metastasis and melanoma recurrence, and a model including these factors predicts these outcomes better than one with just clinical data.
November 2025 in “Journal of Investigative Dermatology” Alpha-MSH affects mitochondrial function, and MC1R mutations may increase skin aging.
70 citations
,
May 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Notch/RBP-J signaling is crucial for proper placement and timing of melanocyte development in hair follicles.
January 2012 in “heiDOK (Heidelberg University)” Dormant melanoma cells in mice interact minimally with memory T cells due to a suppressive tumor environment.
2 citations
,
September 2023 in “PLoS biology” Newly divided skin cells quickly move to join skin structures due to tissue tension and specific signals.
23 citations
,
June 2015 in “Oncology Letters” Adipose-derived stem cell-conditioned medium can reduce melanoma cell growth and spread.
1 citations
,
January 2021 in “Processes” Researchers successfully grew horse skin cells that produce pigment from hair follicle samples.
January 2015 in “OpenBU/Boston University Institutional Repository (Boston University)” Neuropilin 2 may be a biomarker for melanoma and affects melanocyte behavior.
January 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Newly born mesenchymal cells quickly spread out in response to tissue tension during early development.
April 2023 in “Dermatology practical & conceptual” Lenalidomide helps hair follicle stem cells turn into melanocytes, which may improve repigmentation in vitiligo.
Moles may stop growing because of cell cooperation, not just because of aging cells.
84 citations
,
July 2003 in “European journal of biochemistry” Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.
NuMA-microtubule interactions are vital for proper skin structure formation and function.
81 citations
,
October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain genes control the color of human hair by affecting pigment production.