7 citations
,
July 2013 in “Acta Biochimica Polonica” Chemotherapy reduces splenic melanin in mice.
May 2024 in “International journal of molecular sciences” Melatonin cream may help prevent skin damage but its anti-aging and hair growth effects are unclear.
May 2019 in “CINECA IRIS Institutial Research Information System (University of Genoa)” MITF+ melanoma patients are more likely to have multiple melanomas and unique skin patterns.
January 2019 in “DSpace@MIT (Massachusetts Institute of Technology)” Higher PHGDH levels cause unusual melanin buildup in hair follicles.
March 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Fat tissue around hair follicles releases a growth factor that helps hair grow and develop color.
26 citations
,
May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking mTORC1 activity with rapamycin could help increase hair pigmentation and growth, potentially reversing gray hair.
Melatonin applied to the scalp helps treat early-stage hair loss in men and women.
22 citations
,
January 1985 in “Journal of Human Evolution/Journal of human evolution” Human skin and hair color variation is mainly due to melanin produced by a few genes, with melanin protecting against sun damage.
52 citations
,
October 2004 in “Veterinary dermatology” Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.
70 citations
,
May 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Notch/RBP-J signaling is crucial for proper placement and timing of melanocyte development in hair follicles.
January 2026 in “Figshare” Finasteride can cause melasma, especially in people with darker skin.
6 citations
,
August 2019 in “PLOS ONE” Gambogic Amide helps maintain hair color and promotes hair growth.
February 2026 in “Case Reports in Dermatology” Finasteride can cause melasma, especially in people with darker skin.
3 citations
,
December 2016 in “Journal of epidemiological research” Estrogen and androgenic hair increase melanoma risk, especially in European-ancestry individuals.
4 citations
,
October 2021 in “International Journal of Cosmetic Science” Cirsium japonicum flower extract increases melanin production and could help treat depigmentation conditions.
Melatonin helps hair grow.
April 2023 in “Journal of Investigative Dermatology” Blocking casein kinase 1 in skin cells can help melanocyte precursors move better, potentially helping with conditions like vitiligo or gray hair.
April 2023 in “Journal of The American Academy of Dermatology” Some drugs linked to growth hormones may increase the chance of hair loss in women.
9 citations
,
January 2005 in “Experimental Dermatology” Human hair follicles can produce stress hormones like the body's main stress response system.
59 citations
,
April 2016 in “Cell Reports” EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
12 citations
,
September 2022 in “Frontiers in Genetics” Enhancing CD8+ T cell function to induce ferroptosis in tumor cells may help treat skin melanoma.
11 citations
,
January 2016 in “Evidence-based Complementary and Alternative Medicine” Rice bran extract can increase melanin production and may help treat melanin deficiency.
4 citations
,
February 2023 in “International Journal of Stem Cells” The FTO gene hinders stem cells in hair follicles from becoming pigment cells.
24 citations
,
April 2013 in “PLOS ONE” TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.
31 citations
,
March 1965 in “British Journal of Dermatology” Certain chemicals can change hair growth and color.
October 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Thymic peptides can either promote or inhibit human hair growth.
January 2026 in “Figshare” Finasteride can cause melasma, especially in people with darker skin.
Cialis and Finasteride could be repurposed to treat aggressive melanoma.
January 2013 in “วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS)” Safflower extract increases melanin production in certain skin cells without harming them.