57 citations
,
February 1994 in “Experimental dermatology” Melatonin affects mouse skin and may regulate skin functions.
1 citations
,
January 1981 in “Elsevier eBooks” Melatonin stops melanin production after tyrosinase action, with cyclic GMP mimicking this effect.
Melatonin can improve treatment and extend remission for certain skin conditions.
September 2025 in “Indian Dermatology Online Journal” Melatonin, primarily known for regulating circadian rhythms, also provides significant antioxidant, anti-inflammatory, and immunomodulatory benefits, making it a promising treatment for dermatological conditions such as atopic dermatitis, melasma, androgenic alopecia, and psoriasis. It reduces oxidative stress, aids in DNA repair, and offers anti-aging and photoprotective effects. Studies have shown positive outcomes, particularly in androgenic alopecia, where topical melatonin has been effective in promoting hair growth. However, further research is needed to determine optimal dosing, long-term safety, and how it compares to traditional treatments.
220 citations
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August 1988 in “Clinical endocrinology” Melatonin may help with sleep issues, depression, and cancer, but more research is needed.
11 citations
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April 2013 in “SpringerPlus” Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.
10 citations
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May 2020 in “Advances in Polymer Technology” Melatonin-loaded nanoparticles improve antidepressant effects and HPA hormone balance better than regular melatonin.
February 2025 in “Biomolecules” Melatonin can help or hinder hair growth depending on the dose.
December 2023 in “Melatonin research” Nanocarriers make melatonin more effective and reduce side effects.
26 citations
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February 2022 in “Journal of pineal research” Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
9 citations
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January 2005 in “Experimental dermatology” Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
11 citations
,
June 2021 in “Preprints.org” Melatonin may help with atopic dermatitis by reducing inflammation and improving sleep.
53 citations
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July 1981 in “Journal of Endocrinology” α-MSH and cyclic AMP boost melanin production, while cyclic GMP and melatonin reduce it.
4 citations
,
May 2022 in “PeerJ” Melatonin may help hair growth by affecting cell growth and hair-related signaling pathways.
1 citations
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February 2023 in “International Journal of Molecular Sciences” Melatonin, the sleep hormone, can help treat skin conditions like dermatitis, hyperpigmentation, and scalp disorders, and may also aid in skin aging prevention and regeneration. However, it's not recommended for asthma due to its pro-inflammatory effect.
3 citations
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October 1996 in “International Journal of Dermatology” Melatonin can affect skin color, treat skin conditions, and may help with skin cancer.
9 citations
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July 2018 in “European journal of dermatology/EJD. European journal of dermatology” Disrupted sleep patterns can harm skin and hair cell renewal, but melatonin might help.
3 citations
,
November 2022 in “Experimental dermatology” Melatonin may inhibit melanoma growth and has potential as a cancer therapy aid, but its effects on human skin pigmentation need more research.
75 citations
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January 1980 in “Journal of Investigative Dermatology” 1 citations
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January 2013 in “Journal of clinical & experimental dermatology research” Melatonin may help whisker growth in mice.
May 2024 in “Cell proliferation” Melatonin helps hair grow by activating a specific signaling pathway.
1 citations
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April 2023 in “Journal of Animal Science and Biotechnology” Melatonin helps grow more secondary hair follicles in young goats, improving cashmere production.
7 citations
,
April 2014 in “Cell biology international” Melatonin treatment helps improve skin health in postmenopausal rats.
September 2004 in “Experimental dermatology” Melatonin directly affects mouse hair follicles and may influence hair growth.
October 2025 in “Molecular Genetics and Genomics” Melatonin helps regulate hair growth and may treat hair loss.
November 2024 in “Genomics” Melatonin boosts hair growth in cashmere goats by helping certain cells multiply.
July 2023 in “Frontiers in Veterinary Science” Melatonin helps hair grow by activating the RORα receptor in goats.
April 2026 in “Journal of Dermatology Research” The skin communicates with the nervous system, and targeting neurohormones like melatonin and oxytocin could help treat skin issues.
1 citations
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October 2022 in “Research Square (Research Square)” Melatonin helps improve Cashmere goat hair quality by promoting hair follicle growth through a specific cell signaling pathway.