research Progesterone, neurosteroids, and the hormonal basis of catamenial epilepsy
Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.
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research The involvement of androgens in human hair growth
Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.
research Hair aging and anti-aging
Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.
research Increased Expression of TSPEAR in Colorectal Cancer Predicts Poor Prognosis
High TSPEAR levels in colorectal cancer predict worse outcomes.
research Increased Expression of TSPEAR in Colorectal Cancer Predicts Poor Prognosis
High TSPEAR levels in colorectal cancer predict worse outcomes.
research Gender Differences in Facial Rejuvenation
Men and women need different facial rejuvenation treatments due to distinct aging processes and anatomical differences.
research Skin, Genetic Defects, and Aging
Genetic defects and UV radiation cause skin damage and aging.
research A Humanized Mouse Model of Hereditary 1,25-Dihydroxyvitamin D–Resistant Rickets Without Alopecia
Researchers created a mouse model of a type of rickets that does not cause hair loss.
research A Comprehensive Approach in Diagnosing the Polycystic Ovary Syndrome
The document concludes that diagnosing PCOS requires a thorough approach, considering various symptoms and risks, and calls for improved methods to identify PCOS types and prevent diabetes.
research Sexual dysfunction, including hypoactive sexual desire disorder: Diagnosis and treatment recommendations
Testosterone therapy can improve sexual function in women but long-term safety is unclear.
research Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization
Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.
research The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury
Serine is vital for hair follicle stem cells to balance hair growth and skin repair.
research Genetically determined metabolites in allergic conjunctivitis: A Mendelian randomization study
Eight blood metabolites are linked to causing allergic conjunctivitis, offering new ways to predict and treat it.
research Prolactin: an emerging force along the cutaneous–endocrine axis
Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
research Androgenetic Alopecia in Polycystic Ovary Syndrome: A Cutaneous Marker of Systemic Metabo-inflammatory and Endocrine Dysfunction: A Narrative Review
Androgenetic alopecia in PCOS is linked to insulin resistance, inflammation, and genetics, not just hormones.
research Modulating Aging and Aging-related Symptoms Using Endogenous Small Molecules
A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.
research Polycystic ovary syndrome in adolescents
Polycystic Ovary Syndrome (PCOS) in teenagers is a complex condition linked to genetics and environment, often associated with obesity and insulin resistance, and is treated with lifestyle changes and medication.
research Cell type‐specific actions of thyroid hormones in nonalcoholic steatohepatitis and liver fibrosis
Targeting thyroid hormone receptor α in liver cells may help treat liver fibrosis.
research Approach to the Patient: Diagnostic Challenges in the Work Up for Polycystic Ovary Syndrome
Diagnosing PCOS is challenging due to its complex and varied symptoms.
research The Pathobiology of Skin Aging
Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
research Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency
Fatp4 is crucial for healthy skin development and function.
research Exploring the relationship between anastasis and mitochondrial ROS-mediated ferroptosis in metastatic chemoresistant cancers: a call for investigation
Targeting specific molecular pathways may improve treatments for chemoresistant cancers.
research Skinspan: A Holistic Roadmap for Extending Skin Longevity With Evidence‐Based Interventions
The framework suggests sun protection, retinoids, and antioxidants to improve skin longevity.
research Novel anticonvulsive effects of progesterone in a mouse model of hippocampal electrical kindling
Progesterone can reduce seizures without relying on the GABAA receptor pathway.
research The Role of the Mammalian Target of Rapamycin (mTOR) in Pulmonary Fibrosis
mTOR inhibitors may help treat lung fibrosis.
research Remodeling of Root Growth Under Combined Arsenic and Hypoxia Stress Is Linked to Nutrient Deprivation
Combined arsenic and low oxygen stress alters root growth to help plants absorb nutrients.
research Recent omics advances in hair aging biology and hair biomarkers analysis
More research is needed to understand hair aging and develop effective treatments.
research Expression profile analysis of dermal papilla cells mRNA in response to WNT10B treatment
WNT10B affects hair growth by altering gene activity in hair cells.
research Cellular senescence and polycystic ovary syndrome: mechanisms and therapeutic strategies from a new perspective
Targeting senescent cells may offer new treatments for PCOS.
research Pyruvate Kinase M2 Role in Cardiovascular Repair
PKM2 is a promising target for heart repair and regeneration.