November 2025 in “Journal of Investigative Dermatology” Skin-associated cartilage cells can influence hair growth by altering specific signaling pathways.
October 2025 in “International Journal of Innovative Research in Technology” Certain natural ingredients and lifestyle changes can help manage PCOS symptoms by balancing hormones and improving insulin sensitivity.
May 2025 in “Antioxidants” Natural products show promise for treating diseases but need more research to understand and use them effectively.
March 2025 in “Forum Dermatologicum” Metabolic syndrome may worsen certain skin conditions, and managing both together is important.
December 2024 in “ACS Applied Materials & Interfaces” The new hydrogel helps heal diabetic wounds by reducing inflammation and improving tissue repair.
March 2015 in “Plastic and reconstructive surgery” Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
June 2010 in “The Knowledge Bank (The Ohio State University)” Inhibiting retinoic acid activates WNT signaling, potentially aiding hair disorder and skin cancer treatments.
April 2026 in “Biomolecules” New treatments for PCOS using smart drug delivery, metabolic changes, and AI show promise but need more research.
January 2026 in “International Journal of Endocrinology” Lowering HER2 levels with certain drugs may reduce metabolic syndrome risk in women.
408 citations
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January 2017 in “Science” Some wound-healing cells can turn into fat cells around new hair growth in mice.
200 citations
,
October 2009 in “European journal of endocrinology” Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.
169 citations
,
May 2006 in “Genes & Development” Keratin 17 is crucial for normal hair growth by regulating hair cycle transitions with TNFα.
132 citations
,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
91 citations
,
December 2019 in “The EMBO Journal” NEDD4 and NEDD4L help control intestinal stem cells and prevent tumors by breaking down the LGR5 receptor.
61 citations
,
January 2011 in “PloS one” Notch signaling is essential for healthy skin and hair follicle maintenance.
59 citations
,
July 2015 in “Journal of Immunology” Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.
54 citations
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November 2017 in “Scientific Reports” The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.
53 citations
,
January 2011 in “Diabetes” People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
47 citations
,
September 2015 in “Cell Cycle” Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.
44 citations
,
January 2023 in “New Phytologist” FER and TOR signaling help root hair growth in low temperature and low nitrate conditions.
35 citations
,
July 2022 in “Frontiers in Cell and Developmental Biology” Proper mTOR signaling is crucial for healthy skin and preventing skin diseases.
29 citations
,
June 2018 in “Scientific Reports” 15-lipoxygenase helps keep skin healthy by reducing inflammation.
28 citations
,
February 2016 in “F1000Research” Understanding glycans and enzymes that alter them is key to controlling hair growth.
26 citations
,
December 2020 in “Nature metabolism” Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
25 citations
,
November 2017 in “Molecular Medicine Reports” PlncRNA-1 helps hair follicle stem cells grow and develop by controlling a specific cell signaling pathway.
21 citations
,
May 2021 in “Prostate Cancer and Prostatic Diseases” COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.
21 citations
,
July 2019 in “Cardiovascular Research” High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.
21 citations
,
March 2019 in “Experimental Dermatology” Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.
14 citations
,
May 2013 in “American Journal of Physiology-endocrinology and Metabolism” Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.
13 citations
,
January 2016 in “Journal of cosmetology & trichology” Alternative treatments show promise for hair growth beyond traditional methods.